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肾神经消融术治疗高血压的病理生理学基础和临床研究进展

陈艾东 朱国庆

中国医学前沿杂志(电子版)2024,Vol.16Issue(2):1-5,5.
中国医学前沿杂志(电子版)2024,Vol.16Issue(2):1-5,5.DOI:10.12037/YXQY.2024.02-01

肾神经消融术治疗高血压的病理生理学基础和临床研究进展

Pathophysiological basis and clinical progress of renal denervation treatment for hypertension

陈艾东 1朱国庆1

作者信息

  • 1. 南京医科大学 生理学系,江苏 南京 211166
  • 折叠

摘要

Abstract

Hypertension is a chronic cardiovascular disease that seriously threatens human health.Despite the availability of various antihypertensive drugs,most patients'blood pressure cannot reach the ideal level recommended by the guidelines.Excessive sympathetic activation plays an important role in hypertension.Renal denervation(RDN)removes renal nerves including the renal efferent and afferent nerves,thereby reducing sympathetic nerve activity.It has become an important supplement and non-pharmacological treatment for hypertension,especially for the treatment of resistant hypertension.Clinical studies have shown the safety and effectiveness of RDN,which can reduce blood pressure and improve prognosis in patients with resistant hypertension.

关键词

高血压/肾神经/肾动脉交感神经消融术/交感神经活动

Key words

Hypertension/Renal nerve/Renal denervation/Sympathetic activity

引用本文复制引用

陈艾东,朱国庆..肾神经消融术治疗高血压的病理生理学基础和临床研究进展[J].中国医学前沿杂志(电子版),2024,16(2):1-5,5.

基金项目

National Natural Science Foundation of China(32071106,31871148,31571168) 国家自然科学基金(32071106,31871148,31571168) (32071106,31871148,31571168)

中国医学前沿杂志(电子版)

OA北大核心CSTPCD

1674-7372

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