摘要
Abstract
Objective:To explore the effect of ultrasound monitoring of inferior vena cava variability guided fluid resuscitation on hemodynamics and prognostic indicators in patients with septic shock.Method:A total of 100 patients with septic shock who admitted to Jianhu County People's Hospital from January 2020 to January 2023 were selected as the study subjects,they were randomly divided into the control group and the experimental group,with 50 patients in each group.The experimental group was given ultrasound monitoring of inferior vena cava variability guided fluid resuscitation therapy,while the control group was given routine fluid resuscitation therapy.The hemodynamic indexes[mean arterial pressure(MAP),central venous pressure(CVP)and lactic acid level]before resuscitation and 72 h after resuscitation,prognostic indexes[mechanical ventilation time,resuscitation fluid volume,Intensive Care Unit(ICU)stay time,vasoactive drug use time],clinical indexes(6 h resuscitation compliance rate,organ failure rate and 30 d mortality rate),acute physiology and chronic health evaluation Ⅱ(APACHEⅡ)score and sequential organ failure assessment(SOFA)score before treatment and 72 h after treatment were compared between two groups.Result:The lactic acid level in the experimental group at 72 h after resuscitation was lower than that in the control group,the MAP and CVP levels were higher than those in the control group,the mechanical ventilation time,ICU stay time and vasoactive drug use time were shorter than those in the control group,the resuscitation fluid volume was less than that in the control group,the 6 h resuscitation compliance rate was higher than that in the control group,the incidence of organ failure and 30 d mortality were lower than those in the control group,and the APACHEⅡ score and SOFA score at 72 h after treatment were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion:Ultrasound monitoring of inferior vena cava variability guided fluid resuscitation in patients with septic shock can help improve hemodynamics and prognostic indicators,improve the recovery rate,reduce the incidence of organ failure and death,and reduce APACHEⅡ score and SOFA score.关键词
超声监测下腔静脉变异度/液体复苏/脓毒症休克/预后指标Key words
Ultrasound monitoring of inferior vena cava variability/Fluid resuscitation/Sepsis shock/Prognostic indicators
