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首页|期刊导航|中外女性健康研究|拉贝洛尔+硫酸镁对妊娠期高血压的治疗价值及症状改善作用分析

拉贝洛尔+硫酸镁对妊娠期高血压的治疗价值及症状改善作用分析OA

Therapeutic value and symptom improvement of Labetalol + magnesium sulfate in hypertensive pregnancy

中文摘要英文摘要

目的:分析针对妊娠期高血压患者,应用拉贝洛尔+硫酸镁治疗的临床效果.方法:抽取 2020 年 10 月至 2021 年 10 月于本院就诊的妊娠期高血压患者,例数共计 88 例,计算机 1∶1随机数列分布分设组别.单药组(硫酸镁,n=44),联合组(拉贝洛尔+硫酸镁,n=44);比较两组临床效果.结果:用药后联合组收缩压及舒张压均低于单药组,且联合组舒张压及舒张压降低幅度显著高于单药组,数据比较有意义(P<0.05);联合组尿蛋白量低于单药组,炎症因子浓度低于单药组,数据比较有意义(P<0.05);联合组分娩结局指标较单药组均佳,数据比较有意义(P<0.05);联合组不良反应总发生率为 1.91%,单药组为 25.00%,但数据比较无意义(P>0.05).结论:针对妊娠期高血压患者,应用拉贝洛尔+硫酸镁治疗不仅安全性高,也可降低分娩及妊娠风险,于血压控制水平提升有显著增益效果.

Objective:To analyze the clinical effect of labetalol + magnesium sulfate in the treatment of hypertensive patients during pregnancy.Methods:A total of 88 patients with gestational hypertension were selected from 2020.10 to 2021.10 in our hospital.The patients were divided into groups by 1∶1 random sequence distribution.Monotherapy group(magnesium sulfate,n=44)and combination group(Labetalol + magnesium sulfate,n=44);The clinical effect of the two groups was compared.Results:After medication,the systolic blood pressure and diastolic blood pressure of combination group were lower than those of single drug group,and the diastolic blood pressure and diastolic blood pressure of combination group were significantly lower than those of single drug group(P<0.05).The urine protein content and inflammatory factor concentration in combination group were lower than those in monotherapy group(P<0.05).The indexes of delivery outcome in combination group were better than those in monotherapy group,and the data were significant(P<0.05).The total incidence of adverse reactions was 1.91%in combination group and 25.00%in monotherapy group,but the data were significant(P>0.05).Conclusion:For the patients with pregnancy-induced hypertension,the application of labetalol + magnesium sulfate is not only safe,but al-so can reduce the risk of labor and pregnancy,and has a significant gain effect on the improvement of blood pressure control level.

朱晓娜

宁津县计划生育妇幼保健服务中心产二科,山东 德州 253400

临床医学

拉贝洛尔硫酸镁妊娠期高血压分娩妊娠

LabetalolMagnesium sulfateHypertension during pregnancyGive birthPregnancy

《中外女性健康研究》 2024 (003)

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