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HPV、TCT及阴道镜对宫颈癌筛查的临床效果研究OA

Study on the clinical effect of HPV,TCT and colposcopy for cervical cancer screening

中文摘要英文摘要

目的:探讨宫颈癌筛查采用HPV、TCT及阴道镜的效果.方法:选择医院 2021 年 1 月至 2022 年 12 月收治疑似宫颈病变患者 100 例,均接受HPV、TCT检测及阴道镜检查,以病理学检查结果为金标准,分析比较HPV、TCT检测及阴道镜单独与联合检查对宫颈病变的检出率,以及HPV、TCT检测单独与联合检查的诊断效能.结果:该 100 例疑似宫颈病变患者经病理学检查确诊为宫颈病变者 58 例,包括有低度鳞状上皮内病变者 20 例、高度鳞状上皮内病变者 27 例、宫颈癌患者 11 例.HPV、TCT检测及阴道镜联合检查的检出率 100.00%(58/58),分别高于单独HPV、TCT检测与阴道镜检查的检出率,且单独 HPV检测与阴道镜检查的检出率分别为 90.91%(430/473)、90.91%(430/473),高于单独TCT检测的检出率(P<0.05).HPV、TCT联合筛查宫颈癌的准确率、敏感度与阴性预测值分别为 90.91%(430/473)、90.91%(430/473)、90.91%(430/473),分别高于单独 HPV、TCT检测(P<0.05).结论:在宫颈癌筛查中,联合TCT、HPV检测及阴道镜检查可显著的提升筛查准确率,能够及时的对疾病进行确诊并给予针对性的处理,以改善患者预后.

Objective:To explore the efficacy of HPV,TCT and colposcopy for cervical cancer screening.Methods:A total of 100 patients with suspected cervical lesions who were admitted to our hospital from January 2021 to December 2022 were given HPV and TCT tests and colposcopy.Taking the pathological examination results as the gold standard,the detection rates of HPV and TCT tests and colposcopy combined with or without colposcopy for cervical lesions were analyzed and compared,as well as the diagnostic efficacy of HPV and TCT tests combined with or without colposcopy.Results:Fifty-eight of the 100 sus-pected cervical lesions were confirmed as cervical lesions by pathological examination,including 20 cases with low-grade squa-mous intraepithelial lesions,27 cases with high-grade squamous intraepithelial lesions and 11 cases with cervical cancer.The de-tection rates of HPV,TCT and colposcopy were 100.00%(58/58),respectively,higher than those of HPV alone,TCT and col-poscopy.The detection rates of HPV alone and colposcopy were 90.91%(430/473)and 90.91%(430/473),respectively,higher than that of TCT alone(P<0.05).The accuracy,sensitivity and negative predictive value of HPV and TCT combined screen-ing for cervical cancer were 90.91%(430/473),90.91%(430/473)and 90.91%(430/473),respectively,higher than those of HPV and TCT alone(P<0.05).Conclusion:In cervical cancer screening,combined with TCT,HPV testing and colposcopy can significantly improve the accuracy of screening,and timely diagnose the disease and give targeted treatment to improve the prognosis of patients.

张心耸

兖州区人民医院,山东 济宁 272100

临床医学

HPVTCT阴道镜宫颈癌

HPVTCTColposcopyCervical cancer

《中外女性健康研究》 2024 (003)

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