经尿道等离子前列腺剜除术与经尿道前列腺电切术在良性前列腺增生患者中的效果对比OA
Comparison Effect of Transurethral Plasma Kinetic Enucleation of Prostate and Transurethral Resection of Prostate in Patients with Benign Prostatic Hyperplasia
目的:对比经尿道等离子前列腺剜除术(TUKEP)与经尿道前列腺电切术(TURP)在良性前列腺增生(BPH)患者治疗中的应用效果.方法:选取 2022 年 1 月 11 日—2023 年 6 月 20 日镇江市第一人民医院收治的 100 例BPH患者作为研究对象,按照随机数表法将其分为剜除组(采用TUKEP治疗)与电切组(采用TURP治疗),各 50 例.比较两组围手术期指标、下尿路症状指标、血清相关因子水平及并发症发生情况.结果:剜除组手术时间、住院时间、症状消失时间、导尿管留置时间均短于电切组,术中出血量少于电切组,差异有统计学意义(P<0.05);术后 3 个月,两组国际前列腺症状评分(IPSS)、最大尿流量(Qmax)及残余尿量(RV)较术前改善,且剜除组改善幅度大于电切组,差异有统计学意义(P<0.05);术后 3 个月,两组白细胞介素-6(IL-6)、白细胞介素-8(IL-8)及前列腺特异性抗原(TPSA)水平低于术前,且剜除组低于电切组,差异有统计学意义(P<0.05);剜除组并发症发生率(6.00%)低于电切组(22.00%),差异有统计学意义(P<0.05).结论:与TURP相比,TUKEP在BPH的治疗中安全性更高,其不仅具有手术时间短、出血量少、患者恢复快等优点,还能更好地改善尿路功能,降低IL-6、IL-8、TPSA水平,降低并发症发生率.
Objective:To compare the application effect of transurethral plasma kinetic enucleation of prostate(TUKEP)and transurethral resection of prostate(TURP)in the treatment of benign prostatic hyperplasia(BPH).Method:A total of 100 BPH patients who admitted to Zhenjiang First People's Hospital from January 11,2022 to June 20,2023 were selected as the study objects,and they were divided into the enucleation group(given TUKEP treatment)and the electrocision group(given TURP treatment)according to random number table method,50 cases in each group.The perioperative indexes,lower urinary tract symptom indexes,serum related factors and complication rate were compared between two groups.Result:The operation time,hospitalization time,symptom disappearance time and catheter indwelling time in the enucleation group were shorter than those in the electrocision group,and the intraoperative blood loss was less than that in the electrocision group,the differences were statistically significant(P<0.05);at 3 months after operation,the international prostate symptom score(IPSS),maximum urine flow(Qmax)and residual urine volume(RV)of two groups were improved compared with those before operation,and the improvement of the enucleation group were greater than those of the electrocision group,the differences were statistically significant(P<0.05);at 3 months after operation,the levels of interleukin-6(IL-6),interleukin-8(IL-8)and prostate specific antigen(TPSA)in two groups were lower than those before operation,and those in the enucleation group were lower than those in the electrocision group,the differences were statistically significant(P<0.05);the incidence of complications in the enucleation group(6.00%)was lower than that in electrocision group(22.00%),and the difference was statistically significant(P<0.05).Conclusion:Compared with TURP,TUKEP is safer in the treatment of BPH,it not only has the advantages of short operation time,less blood loss and faster recovery of patients,but also can better improve the urinary tract function,reduce the levels of IL-6,IL-8 and TPSA,and reduce the occurrence of complications.
谈健;孙文晋;王正宇;崔飞伦
镇江市第一人民医院 江苏 镇江 212001泰州市第二人民医院
经尿道等离子前列腺剜除术经尿道前列腺电切术良性前列腺增生尿路功能
Transurethral plasma kinetic enucleation of prostateTransurethral resection of prostateBenign prostatic hyperplasiaUrinary tract function
《中外医学研究》 2024 (009)
26-30 / 5
镇江市第一人民医院院级科研基金一般资助项目(Y2020018)
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