摘要
Abstract
Objective:To study the influencing factors and pathogenic characteristics of pulmonary infection in hospitalized patients with rheumatoid arthritis(RA).Method:The clinical data of 118 patients with RA who admitted to Shougang Hospital of Peking University from January 2021 to January 2023 were retrospectively analyzed,the patients were divided into the observation group(with pulmonary infection,n=14)and the control group(without pulmonary infection,n=104)according to the presence or absence of pulmonary infection.The general data of two groups were analyzed,the influencing factors of RA patients with pulmonary infection were analyzed,and the pathogenic characteristics of the observation group were analyzed.Result:The age and smoking proportion of the observation group were higher than those of the control group,and the disease course was longer than that of the control group,the differences were statistically significant(P<0.05);the diabetes proportion,chronic lung disease proportion,white blood cell count(WBC)level,C-reactive protein(CRP)level and glucocorticoid proportion in the observation group were higher than those in the control group,while the platelet count(PLT)level,albumin(ALB)level and disease modifying anti-rheumatic drugs(DMARDs)in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05);the results of logistic analysis showed that the course of disease and glucocorticoids were risk factors for pulmonary infection in RA patients,while DMARDs was protective factors for pulmonary infection in RA patients(P<0.05);a total of 10 strains of pathogenic bacteria were detected in the observation group,including 3 strains(30.00%)of gram-positive bacteria,6 strains(60.00%)of gram-negative bacteria and 1 strain(10.00%)of fungi.Conclusion:At the same time,the course of disease and glucocorticoid drugs are risk factors for pulmonary infection in RA inpatients,while DMARDs is protective factors for pulmonary infection in RA patients.The pathogenic types of pulmonary infection in RA inpatients involve various types of Gram positive bacteria,Gram negative bacteria,and fungi.关键词
类风湿关节炎/肺部感染/病原学特征/影响因素Key words
Rheumatoid arthritis/Pulmonary infection/Pathogenic characteristics/Influence factors
