首页|期刊导航|中外医学研究|头孢哌酮钠舒巴坦钠加左氧氟沙星治疗哮喘伴肺部感染的效果

头孢哌酮钠舒巴坦钠加左氧氟沙星治疗哮喘伴肺部感染的效果OA

Effect of Cefoperazone Sodium and Sulbactam Sodium Combined with Levofloxacin in the Treatment of Asthma with Pulmonary Infection

中文摘要英文摘要

目的:分析哮喘伴肺部感染患者采用头孢哌酮钠舒巴坦钠加左氧氟沙星治疗的效果.方法:选取 2020 年 3 月—2023 年 3 月钟祥市人民医院收治的 152 例哮喘伴肺部感染患者作为研究对象,按照随机数表法以 1∶1 将所有患者分为A组、B组,各 76 例.A组给予头孢哌酮钠舒巴坦钠,B组给予头孢哌酮钠舒巴坦钠联合左氧氟沙星,两组均治疗 14 d.比较两组临床疗效、炎症因子水平、肺功能指标及不良反应发生率.结果:治疗 14 d后,两组不良反应总发生率比较,差异无统计学意义(P>0.05).B组临床治疗总有效率高于A组,差异有统计学意义(P<0.05).与治疗前相比,治疗 14 d后两组炎症因子水平均降低,且B组相对于A组更低,两组肺功能指标均升高,且B组相对于A组更高,差异有统计学意义(P<0.05).结论:哮喘伴肺部感染患者采用头孢哌酮钠舒巴坦钠加左氧氟沙星治疗,可以提高临床疗效,降低炎症因子水平,改善肺功能指标,且不良反应发生风险较低.

Objective:To analyze the effect of Cefoperazone Sodium and Sulbactam Sodium combined with Levofloxacin in the treatment of asthma with pulmonary infection.Method:A total of 152 patients with asthma and pulmonary infection admitted to Zhongxiang People's Hospital from March 2020 to March 2023 were selected as the study objects.According to the random number table method,all patients were divided into group A and group B by 1∶1,with 76 cases in each group.The group A was given Cefoperazone Sodium and Sulbactam Sodium,the group B was given Cefoperazone Sodium and Sulbactam Sodium combined with Levofloxacin,and both groups were treated for 14 d.The clinical efficacy,levels of inflammatory factors,lung function indexes and incidence of adverse reactions were compared between the two groups.Result:After 14 d of treatment,there was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).The total effective rate of treatment of the group B was higher than that of the group A,and the difference was statistically significant(P<0.05).After 14 d of treatment,the levels of inflammatory factors in both groups were decreased compared with those before treatment,and the levels of the group B were lower than those of the group A,the pulmonary function indexes were increased in both groups,and those of the group B were higher than those of the group A,the differences were statistically significant(P<0.05).Conclusion:The treatment of Cefoperazone Sodium and Sulbactam Sodium combined with Levofloxacin in patients with asthma and pulmonary infection can improve clinical efficacy,reduce the level of inflammatory factors,improve lung function indexes,and lower the risk of adverse reactions.

鲍俊桥

钟祥市人民医院 湖北 钟祥 431900

哮喘肺部感染肺功能炎症因子

AsthmaPulmonary infectionPulmonary functionInflammatory factor

《中外医学研究》 2024 (006)

52-55 / 4

10.14033/j.cnki.cfmr.2024.06.013

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