重庆医学2024，Vol.53Issue(7)：1074-1079,6.DOI:10.3969/j.issn.1671-8348.2024.07.022
胆汁淤积发生机制的研究进展
Research progress on occurrence mechanism of cholestasis
摘要
Abstract
Cholestasis is a common clinical syndrome and can be divided into extrahepatic cholestasis(EHC)and intrahepatic cholestasis(IHC)depending on the site of disease.EHC is mainly caused by biliary obstruction due to inflammatory edema,stones,tumors and roundworms,while the IHC occurrence is more complex and the specific pathogenesis is unclear,including primary cholestatic cholangitis,primary sclerosing cholangitis,intrahepatic cholestasis of pregnancy(ICP),IgG4-related sclerosing cholangitis,progressive familial intra-hepatic cholestasis and secondary intrahepatic cholestasis caused by alcoholic liver disease,chronic viral hepatitis,drug-related liver injury,etc.This article mainly summarizes the new developments in the pathogenesis studies of cholestasis and aims to provide a reference for scientific research and clinical workers in this disease.关键词
胆汁淤积/肝内胆汁淤积/胆汁淤积性肝病/综述Key words
cholestasis/intrahepatic cholestasis/cholestatic liver disease/review分类
医药卫生引用本文复制引用
谌洁,章述军..胆汁淤积发生机制的研究进展[J].重庆医学,2024,53(7):1074-1079,6.基金项目
重庆市科卫联合医学科研项目(2020FYYX007). （2020FYYX007）
