首页|期刊导航|国际口腔科学杂志（英文版）|Spatial transcriptomics reveals that metabolic characteristics define the tumor immunosuppression microenvironment via iCAF transformation in oral squamous cell carcinoma

Spatial transcriptomics reveals that metabolic characteristics define the tumor immunosuppression microenvironment via iCAF transformation in oral squamous cell carcinoma

Zheqi Liu Zhenhu Ren Zhen Zhang Yu Zhang Wenkai Zhou Xu Zhang Canbang Peng Tong Ji Xin Zou Zhiyuan Zhang

国际口腔科学杂志（英文版）2024，Vol.16Issue(1)：110-121,12.

国际口腔科学杂志（英文版）2024，Vol.16Issue(1)：110-121,12.DOI:10.1038/s41368-023-00267-8

Spatial transcriptomics reveals that metabolic characteristics define the tumor immunosuppression microenvironment via iCAF transformation in oral squamous cell carcinoma

Zheqi Liu ¹Zhenhu Ren ²Zhen Zhang ³Yu Zhang ³Wenkai Zhou ³Xu Zhang ³Canbang Peng ⁴Tong Ji ⁵Xin Zou ⁶Zhiyuan Zhang²

作者信息

1. Department of Oral and Maxillofacial-Head and Neck Oncology,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine||College of Stomatology,Shanghai Jiao Tong University||National Center for Stomatology||National Clinical Research Center for Oral Diseases||Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology,Shanghai,China||Department of Oral and Maxillofacial Surgery,Zhongshan Hospital,Fudan University,Shanghai,China
2. Department of Oral and Maxillofacial-Head and Neck Oncology,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine||College of Stomatology,Shanghai Jiao Tong University||National Center for Stomatology||National Clinical Research Center for Oral Diseases||Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology,Shanghai,China||Hainan Western Central Hospital,Academician Zhang Zhiyuan Team Innovation Center,Danzhou,China
3. Department of Oral and Maxillofacial-Head and Neck Oncology,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine||College of Stomatology,Shanghai Jiao Tong University||National Center for Stomatology||National Clinical Research Center for Oral Diseases||Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology,Shanghai,China
4. School and Hospital of Stomatology,Kunming Medical University,Kunming,China
5. Department of Oral and Maxillofacial Surgery,Zhongshan Hospital,Fudan University,Shanghai,China
6. Center for Tumor Diagnosis&Therapy,Jinshan Hospital,Fudan University,Shanghai,China||Department of Pathology,Jinshan Hospital,Fudan University,Shanghai,China
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摘要

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Zheqi Liu,Zhenhu Ren,Zhen Zhang,Yu Zhang,Wenkai Zhou,Xu Zhang,Canbang Peng,Tong Ji,Xin Zou,Zhiyuan Zhang..Spatial transcriptomics reveals that metabolic characteristics define the tumor immunosuppression microenvironment via iCAF transformation in oral squamous cell carcinoma[J].国际口腔科学杂志（英文版）,2024,16(1):110-121,12.

基金项目

This study was supported by the Natural Science Foundation of China(82002851),funding of postdoctoral of Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,fundamental research program funding of Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine(JYZZ180),funding of academician workstation in Hainan,Shanghai Anticancer Association EYAS PROJECT(SACA-CY21A01).We would like to thank Accuramed Technology(Shanghai)Limited(https://www.accuramed.com/)and Helixlife Informa-tion Technology Co.,Ltd(Shanghai)(https://www.helixlife.cn/)for the technical supports of the spatial transcriptomic sequencing. （82002851）

国际口腔科学杂志（英文版）

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ISSN：1674-2818

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