神经损伤与功能重建2024，Vol.19Issue(4)：222-226,5.DOI:10.16780/j.cnki.sjssgncj.20230778
微创穿刺血肿清除术联合血肿液化剂治疗脑出血研究进展
Research Progress on the Treatment of Intracerebral Hemorrhage with Minimally Invasive Hematoma Aspiration Combined with Hematoma Liquefaction Agents
摘要
Abstract
Spontaneous intracerebral hemorrhage(ICH)refers to non-traumatic vascular rupture and bleeding within the brain parenchyma.Its harm primarily stems from the space-occupying effect of the intracranial hematoma and secondary damage to the surrounding brain tissue.With the advancement of surgical techniques,the treatment of spontaneous ICH has shifted from traditional craniotomy to minimally invasive surgery(MIS),becoming one of the most promising technologies.MIS is fast,convenient,less traumatic,safe,effective,and cost-effective.One of the core aspects of this technique is the use of biochemical enzymes to liquefy the hematoma,allowing for safe and rapid removal of the hematoma and effectively improving patient outcomes.This article reviews the research progress on the treatment of ICH with MIS combined with hematoma liquefaction agents.关键词
自发性脑出血/微创穿刺血肿清除术/尿激酶/重组组织型纤溶酶原激活剂Key words
spontaneous intracerebral hemorrhage/minimally invasive surgery/urokinase/recombinant tissue plasminogen activator分类
医药卫生引用本文复制引用
喻乙芳,马万宇,任思颖..微创穿刺血肿清除术联合血肿液化剂治疗脑出血研究进展[J].神经损伤与功能重建,2024,19(4):222-226,5.基金项目
国家自然科学基金项目(激活PPARã通过调控MTF1/CTR1通路抑制脑出血后神经元细胞铜死亡促进神经元突起再生修复的机制研究,No.82360253) （激活PPARã通过调控MTF1/CTR1通路抑制脑出血后神经元细胞铜死亡促进神经元突起再生修复的机制研究,No.82360253）
贵州医科大学附属医院2021年博士科研启动基金(激活PPARã调控谷氨酸代谢促进小胶质细胞M2极化修复脑出血后血脑屏障的机制研究,No.gyfybsky-2021-30) （激活PPARã调控谷氨酸代谢促进小胶质细胞M2极化修复脑出血后血脑屏障的机制研究,No.gyfybsky-2021-30）
贵州医科大学附属医院2021年度院级临床研究课题(内侧型小量丘脑出血"楔状征"对患者临床预后的影响,No.2021-GMHCT-016) （内侧型小量丘脑出血"楔状征"对患者临床预后的影响,No.2021-GMHCT-016）
