神经损伤与功能重建2024，Vol.19Issue(4)：239-241,246,4.DOI:10.16780/j.cnki.sjssgncj.20220238
调节小胶质细胞极化状态的受体研究进展
Research Progress on Receptors Regulating the Polarization State of Microglia
张明杰 1段丛妍 1王少峡1
作者信息
- 1. 天津中医药大学/中西医结合学院 天津 301600
- 折叠
摘要
Abstract
Neuroinflammation plays a critical role in the onset,progression,and prognosis of neurodegenerative diseases,in which microglia serve as key modulators.Upon stimulation,microglia are rapidly activated and can be categorized into M1 pro-inflammatory and M2 anti-inflammatory repair phenotypes based on their secreted cytokines and functional states,greatly affecting neuronal survival.The promotion of microglial M1/M2 phenotypic transformation has become a research hotspot in recent years.This article provides an overview of the receptors related to microglial phenotypic transformation.关键词
小胶质细胞/表型转化/受体Key words
microglia/phenotypic transformation/receptors分类
医药卫生引用本文复制引用
张明杰,段丛妍,王少峡..调节小胶质细胞极化状态的受体研究进展[J].神经损伤与功能重建,2024,19(4):239-241,246,4.
