危重症早产儿早期肠道菌群的定植特征及其与临床效果的关系OACSTPCD
Colonization characteristics of early intestinal flora in critically ill premature infants and their relations with clinical effects
目的 探讨危重症早产儿早期肠道菌群的定植特征及其与临床效果的相关性.方法 选取33例28周≤出生胎龄<34周、出生方式为剖宫产、采用配方奶肠道喂养的危重症早产儿,根据治疗效果分为疗效不满意组(A组)18例和疗效满意组(B组)15例.在出生后48 h内采集两组患儿的粪便样本,应用Illumina高通量测序技术对粪便标本中所有细菌的16S rRNA V3～V4区进行DNA测序,分析肠道菌群的物种分类、丰富度和多样性.结果 在门水平上,两组主要优…查看全部>>
To explore the colonization characteristics of early intestinal flora in critically ill premature infants and their correlations with clinical effects.Methods A total of 33 critically ill premature infants,whose gestational age was equal or greater than 28 weeks and less than 34 weeks,birth method was Cesarean section,and who received intestinal feeding with formula milk,were selected,and they were assigned to efficacy dissatisfied group(group A,18 cases)or …查看全部>>
霍开明;吴浪;邓茜;陈海梅;古裕鸟;颜海峰
海南医学院第二附属医院儿科,海南省海口市 570311海南医学院第二附属医院儿科,海南省海口市 570311海南医学院第二附属医院儿科,海南省海口市 570311海南医学院第二附属医院儿科,海南省海口市 570311海南医学院第二附属医院儿科,海南省海口市 570311海南医学院第二附属医院儿科,海南省海口市 570311
临床医学
危重症早产儿肠道菌群定植特征临床效果
Critically illnessPremature infantsIntestinal floraColonization characteristicsClinical effects
《广西医学》 2024 (1)
32-38,7
海南省自然科学基金(820MS147)
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