儿童和青少年颅咽管瘤术后内分泌管理专家共识OACSTPCD
Consensus on endocrine management for children and adolescents with craniopharyngioma surgeries
颅咽管瘤是发生于儿童鞍区的少见良性肿瘤,术后患者可长期存活.因肿瘤及手术常损害下丘脑和垂体功能,导致下丘脑综合征、垂体前叶功能减退症、肥胖、电解质紊乱等一系列功能异常,需内分泌科为主的多学科团队进行长期的精细的激素治疗和随访管理.本共识针对此类人群,围绕围手术期管理、肥胖管理、激素替代、身高增长和青春发育等主题,制定规范化的长期随访管理建议,以提高临床医生的应对水平和患者的健康状态.
Craniopharyngioma is a rare benign tumor mainly occurs in the hypothalamus region of children.Patients may have a long survival after surgery.Tumors or operations may lead to hypothalamic syndrome,hypopituitarism,obesity,and a disturbed electrolytes metabolism.Multidisciplinary medical teams are required to conduct a long-term hormonal therapy and follow-up management.This consensus is aiming for providinge recommendations for perioperative management,obesity,hormonal replacement therapy,linear growth promotion and pubertal develop-ment for pediatric patients.
中国老年保健协会生长发育和性腺疾病分会;茅江峰;伍学焱
北京协和医院内分泌科,北京 100730
临床医学
儿童和青少年颅咽管瘤下丘脑综合征激素替代治疗身高青春发育
children and adolescentscraniopharyngiomahypothalamic syndromehormonal replacement therapyheight promo-tionpubertal development
《基础医学与临床》 2024 (005)
585-598 / 14
国家自然科学基金(81771576,81971375);北京市自然科学基金(7202151,7212080)
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