检验医学与临床2024，Vol.21Issue(8)：1046-1048,1053,4.DOI:10.3969/j.issn.1672-9455.2024.08.005
益气养心方治疗冠心病室性心律失常的疗效及其对心肌缺血的血液流变学指标、CXCL9水平的影响
Effect of Yiqi Yangxin recipe on ventricular arrhythmia of coronary heart disease and its influence on hemorheology index and CXCL9 level of myocardial ischemia
摘要
Abstract
Objective To observe the clinical effect of Yiqi Yangxin recipe on ventricular arrhythmia of cor-onary heart disease and its influence on hemorheology index and CXC chemokine ligand 9(CXCL9)level of myocardial ischemia.Methods A total of 70 patients with ventricular arrhythmia of coronary heart disease ad-mitted to the hospital from June 2021 to December 2022 were selected as the research objects,and they were divided into control group and observation group by random number table method,with 35 cases in each group.The control group was treated with metoprolol tartrate tablets on the basis of conventional symptomat-ic treatment,while the observation group was treated with Yiqi Yangxin recipe on the basis of the control group.Both groups were treated for 4 months.The clinical efficacy,hemorheology index level,serum CXCL9 level and adverse reactions of the two groups were observed.Results The total effective rate of the observa-tion group was higher than that of the control group(P<0.05).After treatment,the whole blood low-shear viscosity,whole blood high-shear viscosity,plasma specific viscosity and fibrin levels of the two groups were lower than those before treatment,and those of the observation group were lower than those of the control group(P<0.05).After treatment,the serum levels of CXCL9 in the two groups were lower than those before treatment,and those in the observation group were lower than those in the control group(P<0.05).No seri-ous adverse reactions were observed in the two groups during treatment,and only very few patients had mild nausea and vomiting.Conclusion Yiqi Yangxin recipe has good clinical efficacy in the treatment of ventricular arrhythmia of coronary heart disease.It can reduce serum CXCL9 level,reduce myocardial damage,improve myocardial hemorheology indexes,promote the recovery of arrhythmia,and has high treatment safety.关键词
益气养心方/冠心病/室性心律失常/心肌缺血/血液流变学/CXC趋化因子配体9/临床疗效Key words
Yiqi Yangxin recipe/coronary heart disease/ventricular arrhythmias/myocardial ische-mia/hemorheology/CXC chemokine ligand 9/clinical efficacy分类
医药卫生引用本文复制引用
黄卫清,杜婷婷,蔡洋..益气养心方治疗冠心病室性心律失常的疗效及其对心肌缺血的血液流变学指标、CXCL9水平的影响[J].检验医学与临床,2024,21(8):1046-1048,1053,4.基金项目
江西省中医药管理局科技计划(2021B693). （2021B693）
