检验医学与临床2024，Vol.21Issue(8)：1049-1053,5.DOI:10.3969/j.issn.1672-9455.2024.08.006
红藤汤加减灌肠治疗粘连性肠梗阻的临床疗效研究
Clinical effect of modified enema with Hongteng decoction on adhesive intestinal obstruction
摘要
Abstract
Objective To investigate the clinical efficacy of modified enema with Hongteng decoction in the treatment of adhesive intestinal obstruction.Methods A total of 86 patients with adhesive intestinal obstruc-tion admitted to the hospital from September 2022 to April 2023 were selected as the research objects,and they were divided into the experimental group and the control group by random number table method,with 43 cases in each group.The control group was treated with conventional western medicine,and the experimental group was treated with enema of Hongteng decoction on the basis of the control group.The TCM syndrome score,neutrophil/lymphocyte ratio(NLR)of blood samples were compared between the two groups before treatment and 3 and 7 days after treatment.The curative effect and incidence of adverse reactions were com-pared between the two groups.The recovery time(gastric tube indwelling time,abdominal pain relief time,ab-dominal distension relief time,first exhaust time,self-defecation time,liquid-air level disappearance time,hos-pitalization time)and the total number of hospitalization due to intestinal obstruction during the study period were compared between the two groups.Results The total effective rate of the experimental group(93.02%)was significantly higher than that of the control group(76.74%),the difference was statistically significant(χ2=4.440,P=0.035).The results of repeated measures analysis of variance showed that there were be-tween-group effects,time effects and interaction effects between groups and time in the TCM syndrome scores of the two groups before treatment,3 d and 7 d after treatment(P<0.05).The gastric tube indwelling time,abdominal pain relief time,abdominal distension relief time,first exhaust time,self-defecation time,liquid-air level disappearance time and the hospitalization time in the experimental group were shorter than those in the control group(P<0.05).The total number of hospitalization due to intestinal obstruction in the experimental group during the study period was less than that in the control group(P<0.05).Repeated measures analysis of variance showed that there were between-group effects,time effects and interaction effects between groups and time in NLR before treatment,3 d and 7 d after treatment in the two groups(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(χ2=0.387,P=0.534).Conclusion The treatment of adhesive intestinal obstruction with Hongteng decoction enema can effectively regulate the level of NLR,promote the rapid relief of clinical symptoms,and improve the therapeutic effect.关键词
粘连性肠梗阻/红藤汤/中药灌肠法/中医证候/临床疗效Key words
adhesive intestinal obstruction/Hongteng decoction/traditional Chinese medicine enema method/TCM syndrome/efficacy分类
医药卫生引用本文复制引用
肖喜风,夏琴琴,丁斌..红藤汤加减灌肠治疗粘连性肠梗阻的临床疗效研究[J].检验医学与临床,2024,21(8):1049-1053,5.基金项目
江西省中医药管理局科技计划(2022B780). （2022B780）
