检验医学与临床2024，Vol.21Issue(8)：1073-1078,6.DOI:10.3969/j.issn.1672-9455.2024.08.011
5 933例更年期泌尿生殖系统综合征女性阴道微生态情况分析
Vaginal microecology analysis of 5 933 women with climacteric genitourinary syndrome
摘要
Abstract
Objective To analyze the vaginal microecology of menopausal genitourinary syndrome(GSM)women and to provide laboratory evidence for clinical diagnosis and treatment.Methods The clinical data of 5 933 postmenopausal women with GSM in the outpatient department of the hospital from June 2020 to July 2023 were retrospectively analyzed.According to age,they were divided into≤50 years old group(2 138 ca-ses),>50-60 years old group(3 043 cases),>60-70 years old group(614 cases),and>70 years old group(138 cases).The morphology of vaginal secretions(including squamous epithelial cells,parabasal epi-thelial cells,white blood cells,red blood cells,pseudohyphae,blastospore,trichomonas,Lactobacillus,coccus and cue cells)were detected by wet slide microscopy,and the vaginal cleanliness was evaluated.The dry chem-ical function indexes(including pH value,leukocyte esterase(LE),hydrogen peroxide(H2O2),sialidase(SNA),proline aminopeptidase(PIP),acetylglucosaminidase(NAG)]were detected by chemical reaction method.Results There were significant differences in the distribution of squamous epithelial cells,parabasal epithelial cells,white blood cells,Lactobacillus,cocci,blastomyces,red blood cells,clue cells and vaginal clean-liness among the four groups(P<0.05).There was no significant difference in the distribution of trichomonas and pseudohyphae among the four groups(P>0.05).There were significant differences in pH,LE and NAG levels among the 4 groups(P<0.05).There was no significant difference in H2O2,SNA and PIP levels among the 4 groups(P>0.05).Conclusion The incidence of GSM is high in postmenopausal women in gynecological clinic,and there are differences in vaginal microecology in different age groups of GSM patients.The analysis of vaginal microecology in different age groups of GSM patients can guide clinicians to accurately treat,reduce the occurrence of repeated infection and improve the quality of life of patients.关键词
更年期泌尿生殖系统综合征/阴道微生态/更年期/年龄段/化学反应法Key words
genitourinary syndrome/vaginal microecology/menopausal period/age group/chemi-cal reaction method分类
医药卫生引用本文复制引用
林蓉蓉,邱德稳..5 933例更年期泌尿生殖系统综合征女性阴道微生态情况分析[J].检验医学与临床,2024,21(8):1073-1078,6.基金项目
江西省中医药管理局科技计划(2021B263). （2021B263）
