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脑出血后神经炎症反应相关生物标志物的研究进展

谷天艳 邹志浩 史清海

检验医学与临床2024,Vol.21Issue(8):1166-1170,5.
检验医学与临床2024,Vol.21Issue(8):1166-1170,5.DOI:10.3969/j.issn.1672-9455.2024.08.030

脑出血后神经炎症反应相关生物标志物的研究进展

Research progress on biomarkers related to neuroinflammatory response after intracerebral hemorrhage

谷天艳 1邹志浩 2史清海3

作者信息

  • 1. 新疆医科大学研究生院,新疆乌鲁木齐 830000
  • 2. 新疆军区总医院神经外科,新疆乌鲁木齐 830000
  • 3. 新疆军区总医院全军临床检验诊断中心,新疆乌鲁木齐 830000
  • 折叠

摘要

Abstract

Intracerebral hemorrhage(ICH)is a common and severe cerebrovascular disease,and the rates of mortality and morbidity are higher.The pathophysiological mechanism of ICH is extremely complex.Neuroinflammatory response plays an important role in the pathophysiological changes of ICH and partici-pates in the early secondary brain injury after ICH and the subsequent repair of brain injury.The neuroinflam-matory response caused by ICH involves the activation of a variety of inflammatory cells and the release of in-flammatory cytokines.In this process,many biomarkers related to neuroinflammatory response after ICH have been widely studied.Dynamic monitoring of inflammation-related biomarkers is helpful to determine the se-verity and prognosis of ICH,and early intervention can reduce the mortality and disability rates.

关键词

脑出血/神经炎症反应/继发性脑损伤/生物标志物/脑血管疾病/病死率/致残率

Key words

intracerebral hemorrhage/neuroinflammatory response/secondary brain injury/biomar-ker/cerebrovascular diseases/mortality rate/disability rate

分类

医药卫生

引用本文复制引用

谷天艳,邹志浩,史清海..脑出血后神经炎症反应相关生物标志物的研究进展[J].检验医学与临床,2024,21(8):1166-1170,5.

基金项目

国家自然科学基金项目(81871020). (81871020)

检验医学与临床

OACSTPCD

1672-9455

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