农药学学报2024，Vol.26Issue(2)：402-407,6.DOI:10.16801/j.issn.1008-7303.2024.0015
桃小食心虫性信息素的合成
Synthesis of the sex pheromone of the peach fruit moth,Carposina sasakii Matsumura
摘要
Abstract
The peach fruit moth(Carposina sasakii Matsumura)is one of China's most serious fruit-boring pests.Sex pheromone-based pest control has the advantages of being highly efficient,environmentally benign and rarely inducing pest resistance.However,the sex pheromone of the peach fruit moth,(Z)-12-decadecadecene-9-one and(Z)-13-decadecene-10-one,is extremely low in the pest.Therefore,it is insufficient for large-scale pest control via artificial extraction.An efficient synthesis of the sex pheromone has been developed via 7 steps including tetrahydro-2H-pyran-2-yl(THP)protection,nucleophilic substitution,Brown P2-Ni reduction,the addition of Grignard reagent and the oxidation with pyridinium dichromate(PDC)from 3-bromopropan-1-ol.Notably,Brown P2-Ni reduction was firstly used to construct a carbon-carbon double bond of the sex pheromone.The total yield was 5%.Our study has the advantages of simple operation and target pheromone with high regional selectivity(Z:E>99:1),which could be used for the green control of the peach fruit moth.关键词
桃小食心虫/性信息素/合成/Brown P2-Ni还原Key words
the peach fruit moth/sex pheromone/synthesis/Brown P2-Ni reduction分类
化学化工引用本文复制引用
王颎琳,孙效,吴建伟,边庆花,王敏,钟江春..桃小食心虫性信息素的合成[J].农药学学报,2024,26(2):402-407,6.基金项目
国家重点研发计划(No.2017YFD0201404).Supported by National Key Technology Research and Development Program of China(No.2017YFD0201404). （No.2017YFD0201404）
