日用化学工业（中英文）2024，Vol.54Issue(4)：484-489,6.DOI:10.3969/j.issn.2097-2806.2024.04.015
高效液相色谱法同时测定化妆品中24种美白成分
Simultaneous determination of 24 whitening components in cosmetics by high performance liquid chromatography
陶薇 1李翔1
作者信息
- 1. 安徽省食品药品检验研究院,安徽 合肥 230051
- 折叠
摘要
Abstract
The study aimed to establish a high performance liquid chromatography(HPLC)method for simultaneous determination of 24 kinds of whitening ingredient in cosmetics.The mobile phase was methanol and monopotassium phosphate solution with gradient elution,the chromatographic column was SHISEIDO MGⅡ C18 column(5 μm,4.6 mm×250 mm),the temperature of the column was set at 25℃with a flow rate of 1.0 mL/min,and the detection wavelengths were 230 nm and 250 nm.The results show that the linear correlation of 24 whitening active ingredients is good in the range of 0.3-608.0 μg/mL,and the linear relationships are all higher than 0.999.The limits of detection are 8.1-438.4 μg/g,the limits of quantitation are 60.4-1 461.4 μg/g and the average recoveries are 87.34%-103.78%,with RSD of 0.16%-4.35%.The method is simple,reliable and can be used for the determination of whitening components in cosmetics.关键词
化妆品/美白成分/高效液相色谱法Key words
cosmetic/whitening components/high performance liquid chromatography分类
化学化工引用本文复制引用
陶薇,李翔..高效液相色谱法同时测定化妆品中24种美白成分[J].日用化学工业（中英文）,2024,54(4):484-489,6.
