四川轻化工大学学报（自然科学版）2024，Vol.37Issue(2)：9-15,7.DOI:10.11863/j.suse.2024.02.02
柠檬酸修饰玻碳电极检测卡比多巴含量研究
Determination of Carbidopa Using Glassy Carbon Electrode Modified with Citric Acid
摘要
Abstract
Four kinds of glassy carbon electrode are prepared to determine carbidopa(CD),which are modified with citric acid,p-phenylenediamine,p-aminobenzene sulfonic acid or L-glutamine by constant potential deposition method.The experiment results show that the glassy carbon electrode modified with citric acid(CA/GCE)exhibits a better selectivity and high sensitivity compared with other electrodes,when it's used to determine the CD.The electron transfer ability of the modified electrode is characterized by using the cyclic voltammetry and electrochemical impedance spectra.The detection ability of CA/GCE electrode for CD in CD-LD compound tablets is investigated by differential pulse voltammetry(DPV).The oxidation peak current at 0.65 V in the phosphate buffer solutions(pH=5.8)is linearly dependent on the CD concentrations in the range of 4.0×10-6～1.0×10-4 mol/L.The proposed electrode shows potential applications in the detection of CD in CD-LD compound tablets,and the relative error is within±5%.关键词
卡比多巴/电化学检测/修饰电极/柠檬酸Key words
carbidopa/electrochemical detection/modified electrode/citric acid分类
化学化工引用本文复制引用
张英,蔡婷婷,张晋原,邹宇,任旺..柠檬酸修饰玻碳电极检测卡比多巴含量研究[J].四川轻化工大学学报（自然科学版）,2024,37(2):9-15,7.基金项目
国家自然科学基金项目(22064005) （22064005）
四川省自然科学基金面上项目(2022NSFSC0103) （2022NSFSC0103）
乡村低成本环境治理技术四川省高校重点实验室开放项目(XCH2022ZB-04) （XCH2022ZB-04）
四川轻化工大学研究生创新基金项目(Y2022027) （Y2022027）
四川轻化工大学大学生创新基金项目(S20221062209) （S20221062209）
