生物医学工程研究2024，Vol.43Issue(2)：129-135,7.DOI:10.19529/j.cnki.1672-6278.2024.02.07
H1型经颅磁刺激线圈结构设计对刺激效果的影响
Influence of H1 transcranial magnetic stimulation coil structure design on stimulation effect
摘要
Abstract
Transcranial magnetic stimulation(TMS)is a non-invasive,painless,low-cost tool in brain stimulation,and has been effective in treating many mental disorders.The H1 coil is a promising tool to achieve deep brain tissue stimulation,which is beneficial for various diseases treatment caused by deep brain tissue lesions.Based on the commercial H1 coil,we proposed a simplified H-shaped coil composed of four turns.Finite element analysis was used to calculate the E field distribution in the spherical head model,the maximum electric field intensity at the depth of 20 mm in the brain and on the brain surface were noted as Emax(20)and Emax(0),separately.The proportion of Emax(20)in Emax(0)was used to characterize the influence of coil structure modification on stimulation depth.Simulation result revealed that,the H-shaped coil's stimulation effect was determined by both the structure and position of the two sets of coils.By adjusting the coil structure,the optimized H1 coil,P(20)and Emax(0)were 75.54%and 32.97 V/m,respective-ly.It is possible to stimulate deep intracranial tissues through reasonable structural design while minimize the maximum electric field in-tensity on the brain surface.关键词
经颅磁刺激/H1型线圈/线圈结构/刺激深度Key words
Transcranial magnetic stimulation/H1 coil/Coil structure/Stimulation depth分类
基础医学引用本文复制引用
吴雅祥,廖绍伟,刘仲武,余红雅..H1型经颅磁刺激线圈结构设计对刺激效果的影响[J].生物医学工程研究,2024,43(2):129-135,7.基金项目
中国博士后科学基金项目(2023M731124). （2023M731124）
