山东医药2024,Vol.64Issue(13):11-15,5.DOI:10.3969/j.issn.1002-266X.2024.13.003
脑死亡器官捐献供体评估和供心选择临床分析
Clinical analysis on donor evaluation and donor heart selection in brain-dead organ donation
摘要
Abstract
Objective To analyze the clinical experience of donor evaluation and heart selection in 73 cases of brain-dead organ donation.Methods The clinical data of 73 pairs of donors and recipients of heart transplantation from brain-dead organ donation were reviewed,the donor was evaluated,the donor heart was selected,and the survival situation of heart transplant recipients and the use of marginal donor hearts were analyzed.Results For potential donors,after deter-mining the brain death status and confirming the donor family's consent to organ donation,donors were evaluated and hearts were selected to maximize the matching of donors and recipients.The success rate of 73 heart transplant recipients was 94.5%(69/73),4 died during perioperative period,and 4 died after 1 year follow-up.Borderline donor:17 patients were aged≥45 years,2 patients had mismatched donor and recipient body mass,1 patient had donor poisoning,and 43 patients had cold ischemia time≥4 h.Most of the recipients were assisted by intra-aortic balloon counterpulsation and/or extracorporeal membrane oxygenation,and were discharged successfully.Conclusions The maximum matching of donor and recipient can achieve satisfactory clinical results in heart transplantation patients.At the same time,appropri-ately relaxing the selection criteria for heart donors and increasing the number of donor hearts will bring good news to many patients waiting for heart transplants.关键词
心脏移植/脑死亡器官捐献/供体评估/供心选择Key words
heart transplantation/brain death organ donation/donor evaluation/heart donor selection分类
医药卫生引用本文复制引用
任琳玮,张熙伟,张辉,张歆杰,刘伟国,王东..脑死亡器官捐献供体评估和供心选择临床分析[J].山东医药,2024,64(13):11-15,5.基金项目
山东省医药卫生科技发展计划项目(2018WS1078). (2018WS1078)