妇儿健康导刊2024，Vol.3Issue(7)：195-198,封3,5.
术前C反应蛋白、血浆纤维蛋白原及血清中性粒细胞/淋巴细胞比值联合检测对儿童复杂性急性阑尾炎的预测价值
Predictive value of combined detection of preoperative C-reactive protein,fibrinogen and serum neutrophil to lymphocyte ratio in children with complicated acute appendicitis
张敏 1冯伟 1陈鹏飞 1侯金平 1王佚1
作者信息
- 1. 重庆医科大学附属儿童医院普外新生儿外科,国家儿童健康与疾病临床医学研究中心,儿童发育疾病研究教育部重点实验室,儿科学重庆市重点实验室,重庆 400014
- 折叠
摘要
Abstract
Objective To investigate the predictive value of combined detection of preoperative C-reactive protein(CRP),fibrinogen(FIB)and serum neutrophil to lymphocyte ratio(NLR)in children with complicated acute appendicitis.Methods The clinical data of 320 children with acute appendicitis admitted to the Department of General and Neonatal Surgery,Children's Hospital of Chongqing Medical University from January to June 2023 were retrospectively analyzed.According to the pathological type,they were divided into complicated acute appendicitis group(149 cases)and uncomplicated acute appendicitis group(171 cases).The levels of white blood cell(WBC),neutrophil(Neu),lymphocyte(Lym),platelet to lymphocyte ratio(PLR),CRP and FIB were compared between the two groups.Multivariate logistic regression was used to analyze the risk factors of complicated acute appendicitis,and the receiver operating characteristic curve was used to analyze the predictive value of combined detection for complicated acute appendicitis in children.Results The preoperative WBC,Neu,CRP,FIB,NLR and PLR in the complicated acute appendicitis group were higher than those in the uncomplicated acute appendicitis group,and Lym was lower than that in the uncomplicated acute appendicitis group(P<0.05).Multivariate logistic regression analysis showed that CRP,FIB and NLR were independent risk factors for complicated acute appendicitis(P<0.05).The area under the curve of CRP,FIB and NLR combined detection of complicated acute appendicitis was larger than that of CRP,FIB and NLR alone(P<0.05).Conclusion The combined detection of FIB,CRP and NLR has a high predictive value for complicated acute appendicitis in children,which can provide a basis for early clinical evaluation of the severity of acute appendicitis.关键词
儿童复杂性急性阑尾炎/C反应蛋白/纤维蛋白原/中性粒细胞/淋巴细胞比值/预测价值Key words
Complicated acute appendicitis in children/C-reactive protein/Fibrinogen/Neutrophil to lymphocyte ratio/Predictive value分类
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张敏,冯伟,陈鹏飞,侯金平,王佚..术前C反应蛋白、血浆纤维蛋白原及血清中性粒细胞/淋巴细胞比值联合检测对儿童复杂性急性阑尾炎的预测价值[J].妇儿健康导刊,2024,3(7):195-198,封3,5.
