摘要
Abstract
Objective To analyze the changes and trends in the burden of cardiovascular diseases(CVD)in China from 1990 to 2019,providing reference to promoting early prevention,treatment,and health management strategies for patients with CVD in China.Methods The study utilized estimates of the burden of CAD in China from Global Burden of Disease Study 2019(GBD 2019)by the Institute for Health Metrics and Evaluation,University of Washington to compare and analyze the trends of crude mortality,standardized mortality,and disability-adjusted life years(DALYs)for CVD in China and globally from 1990 to 2019,and Joinpoint regression model was applied to analyze the average annual percentage change(AAPC)and other indicators.Results From 1990 to 2019,the number of deaths,crude mortality and DALYs for CVD in China increased from 2 423 990,204.78/105 and 5 091.03/105 to 4 584 273,322.30/105 and 6 463.47/105,respectively.The standardized mortality and standardized DALYs decreased from 381.21/105 and 7 412.81/105 in 1990 to 276.94/105 and 4 938.38/105 in 2019.From 1990 to 2019,trend analysis revealed an annual average increase of 1.81%in the crude mortality(95%CI=1.68%-1.94%,P<0.01),a yearly decrease of 0.89%in the standardized mortality(95%CI=-1.02%--0.77%,P<0.01),an annual increase of 1.01%in DALYs(95%CI=0.90%-1.11%,P<0.01),and a yearly decrease of 1.26%in the standardized DALYs(95%CI=-1.35%--1.17%,P<0.01).The trends in crude mortality,standardized mortality,and DALYs for both males and females were consistent with the overall trend.DALYs in people under 70 years old increased annually[AAPC(95%CI)=0.58%(0.46%-0.71%),P<0.01],while DALYs in people over 70 years old showed a yearly decline[AAPC(95%CI)=-0.50%(-0.62%--0.38%),P<0.01].From 1990 to 2019,China's standardized DALYs rate for CVD was much higher than that in countries with high sociodemographic index(SDI),surpassing global levels after 2000 and exceeding the levels of countries with medium-high SDI since 2011.Conclusion Based on the current situation and trends in the burden of CVD in China,implementing precise health management for different populations will help to achieve the goals of healthy aging and healthy China 2030.关键词
心血管疾病/疾病负担/伤残调整生命年/死亡率/趋势分析Key words
Cardiovascular diseases/Disease burden/Disability-adjusted life years/Mortality/Trend analysis
