新医学2024，Vol.55Issue(4)：270-274,5.DOI:10.3969/j.issn.0253-9802.2024.04.006
线粒体动力学相关蛋白与缺血性脑卒中研究进展
Research progress in mitochondrial dynamics-related proteins and ischemic stroke
摘要
Abstract
Ischemic stroke is a common acute cerebrovascular disease in clinical practice,which poses a severe threat to human health.In recent years,with deepening understanding of ischemic stroke,significant progress has been made in the diagnosis and treatment.However,current treatments for ischemic stroke are partially limited due to extremely complex pathological mechanisms.Studies have shown that mitochondrial dysfunction plays an important role in the pathogenesis of ischemic stroke.Therefore,modulation of mitochondrial function through mitochondrial dynamics is essential to ameliorate the damage of cerebral ischemic neuronal cells.In this article,the molecular mechanism of mitochondrial dynamics and its role in ischemic stroke were reviewed,aiming to provide useful reference for the treatment of ischemic stroke.关键词
缺血缺氧/线粒体动力学/氧化应激/炎症反应/细胞凋亡/坏死性凋亡/铁死亡Key words
Ischemia and hypoxia/Mitochondrial dynamics/Oxidative stress/Inflammatory reaction/Apoptosis/Necroptosis/Ferroptosis引用本文复制引用
李婷婷,王钦鹏,刘晓庆,蔡珂,魏阳阳,梁成..线粒体动力学相关蛋白与缺血性脑卒中研究进展[J].新医学,2024,55(4):270-274,5.基金项目
甘肃省科技厅自然科学基金(20210405JCC1549) （20210405JCC1549）
甘肃省神经病学重点实验室(20JR10RA766) （20JR10RA766）
