医药导报2024，Vol.43Issue(5)：717-721,5.DOI:10.3870/j.issn.1004-0781.2024.05.008
交联密度对五层共挤输液用膜性能的影响
Effect of Crosslinking Density on the 5-Layer Co-extrusion Film for Infusion
吴熊 1杨静 1魏七一 1徐赛 1宋小东 1王寅 1胡敏 2赵霞3
作者信息
- 1. 湖北华强科技股份有限公司,宜昌 443000
- 2. 湖北省药品监督检验研究院,武汉 430075
- 3. 中国食品药品检定研究院,北京 100050
- 折叠
摘要
Abstract
Objective To analyze the influence of different crosslinking densities on the performance of 5-layer co-ex-trusion film for infusion.Methods The 5-layer co-extrusion film for infusion samples with different crosslinking densities were prepared using different irradiation conditions.By examining the tensile performance,thermal sealing performance,transmittance,pH value and other indicators,the effects of different crosslinking densities on the physical,chemical,and usage properties of the 5-layer co-extrusion film for infusion were analyzed.Results The results show that the mechanical properties,optical properties and heat sealing properties of the 5-layer co-extrusion film for infusion membrane are improved to a certain extent with the in-crease of the crosslinking density.When the gel content reaches more than 60%,the performance of the 5-layer co-extrusion film for infusion membrane is more excellent.Conclusion It is important to choose the appropriate irradiation process for the prop-erties of 5-layer co-extrusion film for infusion membrane.关键词
五层共挤输液用膜/交联密度/凝胶含量/湿热灭菌Key words
5-Layer co-extrusion film for infusion/Crosslinking density/Gel content/Steam sterilization分类
医药卫生引用本文复制引用
吴熊,杨静,魏七一,徐赛,宋小东,王寅,胡敏,赵霞..交联密度对五层共挤输液用膜性能的影响[J].医药导报,2024,43(5):717-721,5.
