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β-谷甾醇对肿瘤的防治作用及其机制研究进展

张文文 向施 陈慧 杨潮

医药导报2024,Vol.43Issue(5):757-761,5.
医药导报2024,Vol.43Issue(5):757-761,5.DOI:10.3870/j.issn.1004-0781.2024.05.014

β-谷甾醇对肿瘤的防治作用及其机制研究进展

Research Progress on the Protective Effects and Mechanism of β-sitosterol in the Prevention and Treatment of Cancer

张文文 1向施 1陈慧 1杨潮1

作者信息

  • 1. 江西中医药大学癌症研究中心,南昌 330004
  • 折叠

摘要

Abstract

β-sitosterol,a natural steroid compound,is widely used in the pharmaceutical and food industries due to its unique biological activity and physicochemical properties.As an important component of the eukaryotic cell membrane,β-sitosterol not only has an excellent free radical scavenging effect,but also functions in the chemical prevention of diseases such as hyperlipi-demia,atherosclerosis,and inflammation.In recent years,studies have shown that β-sitosterol has excellent inhibitory effects on va-rious cancers,including liver,stomach,colon,lung,and breast cancer.These suggest that β-sitosterol has great potential for preven-ting and treating cancer.This article summarised the anticancer effect and molecular mechanism of β-sitosterol to provide a refer-ence for further understanding its anticancer effect and its potential clinical application in cancer treatment.

关键词

β-谷甾醇/癌症/分子机制/线粒体凋亡途径

Key words

β-sitosterol/Cancer/Molecular mechanism/Mitochondrial apoptosis pathway

分类

医药卫生

引用本文复制引用

张文文,向施,陈慧,杨潮..β-谷甾醇对肿瘤的防治作用及其机制研究进展[J].医药导报,2024,43(5):757-761,5.

基金项目

江西中医药大学中西医结合一级学科(江西省双一流学科) (江西省双一流学科)

江西中医药大学校级研究生创新专项资助项目(JZYC22S20). (JZYC22S20)

医药导报

OA北大核心CSTPCD

1004-0781

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