临床研究2024，Vol.32Issue(5)：109-112,4.DOI:10.12385/j.issn.2096-1278(2024)05-0109-04
孕激素联合宫腔镜等离子电切术治疗子宫内膜息肉的临床效果
Clinical Efficacy of Progesterone Combined with Hysteroscopic Plasma Resection in the Treatment of Endometrial Polyps
摘要
Abstract
Objective To explore the clinical efficacy of progesterone combined with hysteroscopic plasma resection in patients with endometrial polyps(EP).Methods A total of 90 EP patients treated at Puyang Oilfield General Hospital from January 2020 to July 2023 were selected.They were randomly divided into a study group(n=45)and a control group(n=45).The control group was treated with hysteroscopic plasma resection,while the study group was treated with progesterone combined with hysteroscopic plasma resection.The menstrual volume,uterine condition,laboratory examination indicators,adverse reactions,and recurrence rate were compared between the two groups.Results Three months after surgery,both groups showed a decrease in menstrual volume,reduction in endometrial thickness,and decreased pulsatility index(PI)and resistance index(RI)levels,with statistically significant differences(P＜0.05).The study group had less menstrual volume,thinner endometrial thickness,and lower PI and RI levels compared to the control group,with statistically significant differences(P＜0.05).Three months after surgery,both groups showed a decrease in fibrinogen(FIB)levels and an increase in hematocrit(HCT)and hemoglobin(Hb)levels,with statistically significant differences(P＜0.05).The study group had lower FIB levels and higher HCT and Hb levels compared to the control group,with statistically significant differences(P＜0.05).The incidence of adverse reactions in the study group(6.67%)was lower than that in the control group(22.22%),with statistically significant differences(P＜0.05).At 6 months of follow-up,the recurrence rate in the study group(8.89%)was lower than that in the control group(26.67%),with statistically significant differences(P＜0.05).Conclusion Progesterone combined with hysteroscopic plasma resection for the treatment of EP can reduce menstrual volume,improve FIB,HCT,and Hb levels,improve uterine condition,and reduce the incidence of adverse reactions and recurrence rate of EP.关键词
子宫内膜息肉/宫腔镜等离子电切术/孕激素/临床效果Key words
endometrial polyps/hysteroscopic plasma resection/progesterone/clinical efficacy分类
医药卫生引用本文复制引用
郭子楠,王艳虹..孕激素联合宫腔镜等离子电切术治疗子宫内膜息肉的临床效果[J].临床研究,2024,32(5):109-112,4.基金项目
2018年度河南省医学科技攻关计划联合共建项目(2018020968). （2018020968）
