非O1/O139群霍乱弧菌致肝硬化失代偿期患者血流感染1例OA北大核心CSTPCD

A 58-year-old male patient with decompensated cirrhosis after hepatitis B and type n diabetes for 12 years was admitted to hospital due to abdominal distension,edema and oliguria in recent one month.During hospi-talization period,the patient experienced chills and fever,blood specimens were taken for culture,empirical anti-in-fection treatment with cefoperazone/sulbactam was given.The diagnosis of bloodstream infection caused by non-O1/O139 Vibrio cholerae was confirmed,antimicrobial susceptibility testing indicated that cefoperazone/sulbactam was sensitive,current antimicrobial agent was continued,cefoperazone/sulbactam 3 g q12h was changed to 3 g q8h treatment.After 10 days,the patient had no fever,blood and fecal cultures were negative for Vibrio cholerae,con-dition was improved and patient was discharged from the hospital.