中国输血杂志2024，Vol.37Issue(4)：439-443,5.DOI:10.13303/j.cjbt.issn.1004-549x.2024.04.011
2021-2022年广州地区献血人群ABO血型筛查结果分析
ABO blood group screening results among blood donors in Guangzhou from 2021 to 2022
摘要
Abstract
Objective To investigate the distribution of ABO and RhD blood groups among voluntary blood donors in Guangzhou,in order to ensure clinical blood safety and better serve blood donors.Methods Routine ABO and RhD blood group screening tests were carried out among voluntary blood donors from January 2021 to December 2022.The composition ratio of ABO blood group was statistically analyzed.The samples with discrepancy between forward and reverse blood group-ing and negative RhD blood group samples were further verified by serological test to analyze the ABO subtypes and the rea-sons for missed detection.Results A total of 749123 blood samples were screened from January 2021 to December 2022,and 513291 samples were collected after excluding repeat blood donors,with the ABO blood groups as 208126(40.55%)of O type,138859(27.05%)of A type,130987(25.52%)of B type and 35319(6.88%)of AB type.The screening re-sults showed discrepancy between forward and reverse blood grouping in 506 samples,of which 58 were with weak/non-e-rythrocyte reaction,16 with erythrocyte reaction,215 with weak/non-serum reaction,and 217 with serum reaction.Further serological test indicated that 44 samples were ABO subtypes,among which 13 were subtype A,26 subtype B,5 subtype AB and 3 B(A)and 14 Bombay-like blood group.The blood group with the highest missed detection rate in repeat blood donors were A3/B3 subtype(68.42%).A total of 128 unexpected antibody positive samples were detected among 513291 samples A total of 2277 samples were screened negative for RhD blood type,of which 2188 were confirmed to be Rh nega-tive(2188/513291,0.43%),89 were D variants(89/513291,0.02%,)and 30 were detected with unexpected antibod-ies(30/2188,1.37%).Conclusion The ABO blood group distribution of blood donors in Guangzhou is O>A>B>AB,and the proportion of RhD negative population is 0.43%,slightly highter than 0.3%-0.4%of Han population nationwide.The ABO blood group subtype is dominated by B subtype.The detection rate and missed detection rate of A3/B3 subtypes in routine blood group tests are the highest.关键词
ABO血型/RhD血型/正反不一致血型/无偿献血者Key words
ABO blood group/RhD blood group/discrepancy between forward and reverse blood grouping/voluntary blood donors分类
医药卫生引用本文复制引用
刘旭映,黄伯泉,廖芬芳,李仲平,梁浩坚,杜荣松,谢君谋,黄爱琼,王淏..2021-2022年广州地区献血人群ABO血型筛查结果分析[J].中国输血杂志,2024,37(4):439-443,5.基金项目
广州市医学重点学科(2021-2023) （2021-2023）
广州市科技计划项目(2023A03J0996) （2023A03J0996）
广州市卫生健康科技项目(20231A011074) （20231A011074）
