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治疗性单采红细胞罕见不良反应2例OACSTPCD

Rare adverse reactions to therapeutic erythrocytes apheresis:a report of two cases

中文摘要英文摘要

目的 通过对 2 例治疗性单采红细胞患者发生的罕见不良反应的分析,探讨治疗性单采红细胞更多地排除标准及不良反应的可能性.方法 2 例有治疗性单采红细胞适应证的患者,使用单采技术从患者体内采集出红细胞保存备用或弃去.结果 其中 1 例采集后出现持续性房颤及痛风发作;1 例采集中出现持续性低血压及采后血红蛋白的持续降低.结论 严格掌握治疗性单采红细胞的排除标准,加强房颤及痛风患者采集全过程监测,对减少不良反应的发生至关重要.

Objective To investigate additional exclusion criteria for therapeutic apheresis erythrocytes and the possi-bility of adverse reactions by analyzing the occurrence of rare adverse reactions in two patients who underwent therapeutic e-rythrocytes apheresis.Methods Erythrocytes were harvested by apheresis from two patients with indications for therapeutic erythrocytes collection for preservation or discarding.Results One case experienced persistent atrial fibrillation and a gout attack after the collection,while another case experienced persistent hypotension during the collection and a subsequent re-duction in haemoglobin levels after collection Conclusion To reduce the incidence of adverse reactions,it is essential to have strict exclusion criteria for therapeutic erythrocytes apheresis and to enhance the monitoring of whole collection process in patients with atrial fibrillation and gout.

吴玲;甘新宇;谭强;张利;彭涛

西部战区总医院 输血医学科,四川 成都 610083

临床医学

治疗性单采红细胞排除标准不良反应

therapeutic erythrocytes apheresisexclusion criteriaadverse reactions

《中国输血杂志》 2024 (004)

462-465 / 4

10.13303/j.cjbt.issn.1004-549x.2024.04.015

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