摘要
Abstract
Objective:To compare the clinical effects of fluid resuscitation therapy under pulse indicator continuous cardiac output(PiCCO)and central venous pressure(CVP)monitoring in patients with septic shock(SS)complicated with severe acute respiratory distress syndrome(ARDS).Method:A total of 100 patients with SS complicated with severe ARDS admitted to the First Affiliated Hospital of Xiamen University from January 2018 to December 2022 were selected and divided into study group(n=50)and control group(n=50)according to random number table method.The control group was given liquid resuscitation therapy under CVP monitoring,and the study group was given liquid resuscitation therapy under PiCCO monitoring.The rate of achievement of resuscitation goal,vital sign,metabolic indexes and sequelae situation were compared between the two groups.Result:After 6 h of treatment,the rate of achievement of resuscitation goal of the study group was higher than that of the control group,the difference was statistically significant(P<0.05).After 24 h of treatment,urine volume(UO)and mean arterial pressure(MAP)increased and heart rate(HR)decreased in both groups,and UO and MAP in the study group were higher than those in the control group,and HR in the study group was lower than that in the control group,the differences were statistically significant(P<0.05).After 24 h of treatment,central venous blood oxygen saturation(ScvO2)increased and lactate(Lac)levels decreased in both groups,and ScvO2 in study group was higher than that in control group,Lac in study group was lower than that in control group,the differences were statistically significant(P<0.05).The vasoactive drug use time,antibiotic use time,mechanical ventilation time and ICU stay time in the study group were shorter than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Compared with CVP monitoring,liquid resuscitation therapy under PiCCO monitoring for patients with SS complicated with severe ARDS can improve the rate of achievement of resuscitation goal,maintain vital sign,improve metabolic indexes,and promote the recovery of patients.关键词
脓毒症休克/重度急性呼吸窘迫综合征/脉搏指示连续心排血量/中心静脉压/液体复苏Key words
Septic shock/Severe acute respiratory distress syndrome/Pulse indicator continuous cardiac output/Central venous pressure/Liquid resuscitation
