中国医学创新2024，Vol.21Issue(9)：16-21,6.DOI:10.3969/j.issn.1674-4985.2024.09.004
经皮肾镜碎石取石术与输尿管软镜钬激光碎石术在肾和输尿管结石中的应用效果对比
Comparison of the Application Effect of Percutaneous Nephrolithotomy and Flexible Ureteroscope Holmium Laser Lithotripsy in Renal and Ureteral Calculi
摘要
Abstract
Objective:To compare the effect of percutaneous nephrolithotomy(PCNL)and flexible ureteroscope holmium laser lithotripsy(FURL)in the treatment of renal and ureteral calculi.Method:A total of 60 patients with kidney and ureteral calculi admitted to Dexing People's Hospital from March 2019 to February 2022 were selected as the study objects and randomly divided into control group and observation group,with 30 cases in each group.The control group received PCNL treatment,and the observation group received FURL treatment.Both groups were followed up for 1 months after surgery.Operation related indexes,stress response,renal function,quality of life and complications were compared between the two groups.Result:There were no significant differences in stone clearance rate and operation time between the two groups(P>0.05).The intraoperative bleeding volume in the observation group was(20.46±2.17)mL,less than(43.59±3.48)mL in the control group,the hospital stay in the observation group was(3.84±0.52)d,shorter than(5.72±1.03)d in the control group,the incidence of complications in the observation group was 6.67%(2/30),lower than 30.00%(9/30)in the control group,the differences were statistically significant(P<0.05).Before surgery,there were no significant differences in the levels of cortisol(Cor),adrenocorticotropic hormone(ACTH),norepinephrine(NE),epinephrine(E),serum creatinine(Scr),blood urea nitrogen(BUN)and scores of each dimension of 36-item short form health survey(SF-36)between the two groups(P>0.05).After surgery,the Cor,ACTH,NE,E,Scr and BUN in the observation group respectively was(235.97±14.21)nmol/L,(36.97±3.84)ng/L,(756.75±38.73)pmol/L,(483.42±25.59)pmol/L,(97.69±10.54)μmol/L,(6.53±1.81)mmol/L,were lower than(341.86±18.75)nmol/L,(48.82±4.15)ng/L,(839.84±40.76)pmol/L,(571.69±28.96)pmol/L,(108.72±12.76)μmol/L,(7.89±2.43)mmol/L in the control group,scores of each dimension of SF-36 respectively was(79.87±4.12),(80.23±4.08),(79.64±3.76),(78.63±3.98),(78.73±3.41),(79.64±3.97),(80.36±4.01),(82.63±4.28)scores,were higher than(71.35±3.46),(74.84±3.59),(70.75±3.18),(72.57±3.49),(72.49±2.95),(71.85±3.28),(73.59±3.22),(76.59±3.47)scores in the control group,the differences were statistically significant(P<0.05).Conclusion:PCNL and FURL in the treatment of patients with renal and ureteral calculi can achieve excellent stone clearance effects,but FURL has less trauma to the body,less stress response,less damage to patients'kidney function,and helps patients to recover quickly after surgery,thus improving their quality of life,and has fewer complications.关键词
肾结石/输尿管结石/经皮肾镜碎石取石术/输尿管软镜钬激光碎石术Key words
Renal calculus/Ureteral calculi/Percutaneous nephrolithotomy/Flexible ureteroscope holmium laser lithotripsy引用本文复制引用
汪涛,罗泽权,汪海燕..经皮肾镜碎石取石术与输尿管软镜钬激光碎石术在肾和输尿管结石中的应用效果对比[J].中国医学创新,2024,21(9):16-21,6.基金项目
上饶市科技指导计划项目(2022CZDX111) （2022CZDX111）
