摘要
Abstract
Objective:To explore influence of Recombinant Human Interferon α1b Spray combined with Budesonide atomization inhalation on the clinical comprehensive efficacy of children with recurrent upper respiratory tract infection.Method:From January to December 2022,90 children with recurrent upper respiratory tract infections who received treatment at Children's Hospital of Quanzhou Maternal and Child Health Hospital were selected as the study subjects.They were divided into an observation group(n=45)and a control group(n=45)by random number table method.The control group received Budesonide atomization inhalation treatment,while the observation group received Recombinant Human Interferon α1b Spray combined with Budesonide atomization inhalation therapy.The disappearance time of clinical symptoms,treatment effectiveness,immune function indicators and IL-6 between the two groups were observed and compared.Result:The disappearance time of various clinical symptoms in the observation group were shorter than those in the control group,the differences were statistically significant(P<0.05).The effective rate of treatment in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).Before treatment,there were no statistically significant differences in various immune function indicators and IL-6 between the two groups(P>0.05);after treatment,the levels of IgA and IgG in both groups were significantly increased,while the levels of specific IgE were significantly reduced,the observation group showed more significant changes,the differences were statistically significant(P<0.05);after treatment,the IL-6 levels in the two groups were significantly reduced,and the observation group had a more significant change,the differences were statistically significant(P<0.05).Conclusion:Recombinant Human Interferon α1b Spray combined with Budesonide atomization inhalation for repeated upper respiratory tract infections can significantly improve the treatment effect,quickly relieve clinical symptoms,further improve immune function and alleviate inflammatory reaction.关键词
重组人干扰素α1b/布地奈德/雾化吸入/反复上呼吸道感染Key words
Recombinant Human Interferonα1b/Budesonide/Atomization inhalation/Recurrent upper respiratory tract infection
