中国医学创新2024，Vol.21Issue(9)：143-146,4.DOI:10.3969/j.issn.1674-4985.2024.09.032
小儿肺炎支原体肺炎并发消化道系统损害的相关影响因素分析
Analysis of Related Influencing Factors of Digestive Tract System Damage in Mycoplasma Pneumoniae Pneumonia in Children
摘要
Abstract
Objective:To investigate the related influencing factors of digestive tract system damage in mycoplasma pneumoniae pneumonia in children.Method:Clinical data of 132 children with mycoplasma pneumoniae pneumonia admitted to Affiliated Maternity and Child Health Care Hospital of Nantong University from January 2020 to March 2023 were retrospectively analyzed,and they were divided into digestive system damage group(n=35)and non digestive system damage group(n=97)according to whether complicated with digestive tract system damage.General data of the children were collected,including sex,age,weight,fever course,disease course,time when macrocyclic lactones began to be used,time when glucocorticoid began to be used,erythrocyte sedimentation rate(ESR),C reactive protein(CRP)level,white blood cell(WBC)level,and the percentage of neutrophil.Univariate analysis was carried out for the general data,and multivariate logistic regression analysis was carried out for the factors with statistical difference.Result:Among 132 children with mycoplasma pneumoniae infection,35 cases of digestive tract damage,the incidence rate was 26.52%(35/132).Univariate analysis showed that gender,body weight,disease course,glucocorticoid initiation time,ESR,WBC,percentage of neutrophils were compared between the two groups,the differences were not statistically significant(P>0.05).There were statistically significant differences in age,course of fever,start time of macrocyclic lactones and CRP level between the two groups(P<0.05).logistic regression analysis showed that age≤3 years old,duration of fever≥7 d,time of macrocyclic lactones drug use≥3 d,CRP≥10 mg/L were independent risk factors for mycoplasma pneumoniae infection complicated with digestive tract damage in children(OR>1 and P<0.05).Conclusion:Digestive tract system damage in children with mycoplasma pneumoniae pneumonia is associated with age≤3 years old,duration of fever≥7 d,duration of macrocyclic lactones drug use≥5 d,CRP≥10 mg/L.关键词
小儿肺炎支原体肺炎/消化道系统损害/影响因素/炎症水平/大环内酯类Key words
Mycoplasma pneumoniae pneumonia in children/Digestive tract system damage/Influencing factors/Inflammation levels/Macrocyclic lactones引用本文复制引用
钱元原,季卫刚,陈艳艳,张娟..小儿肺炎支原体肺炎并发消化道系统损害的相关影响因素分析[J].中国医学创新,2024,21(9):143-146,4.基金项目
2020年度南通市市级科技计划项目(JCZ20018) （JCZ20018）
