中国医学科学院学报2024，Vol.46Issue(2)：154-160,7.DOI:10.3881/j.issn.1000-503X.15826
H2FPEF和HFA-PEFF评分在我国射血分数保留心力衰竭及射血分数保留心力衰竭合并心房颤动患者中的适用性分析
Applicability of H2 FPEF and HFA-PEFF Scores in Chinese Patients Suffering From Heart Failure With Preserved Ejection Fraction and Heart Failure With Preserved Ejection Fraction Complicated With Atrial Fibrillation
摘要
Abstract
Objective To analyze the diagnostic values of H2FPEF and HFA-PEFF scores for heart failure with preserved ejection fraction(HFpEF)and HFpEF complicated with atrial fibrillation(HFpEF-AF)in Chinese patients and explore the related factors.Methods A cross-sectional study was conducted.A total of 835 consecutive HFpEF patients treated in the Department of Geriatric Cardiology,the First Hospital of Lanzhou Uni-versity from 2009 to 2020 were selected and assigned to a HFpEF-AF group(n =267)and a HFpEF group(n = 568)according to the presence of AF or not.HFA-PEFF and H2FPEF scores were used for retrospective diagnosis and the diagnostic consistency of the two scores was assessed.One hundred and thirty-six healthy volunteers with age and sex matching the patients during the same period were selected as healthy controls.The receiver operating characteristic(ROC)curves were established for H2FPEF and HFA-PEFF scores in diagnosing HFpEF-AF and HFpEF,on the basis of which the diagnostic performance of the two scores was evaluated.Results There was no difference in the HFA-PEFF score between the two groups(P =0.070).However,the HFpEF-AF group had higher mean H2FPEF score and higher proportion of patients with the score no less than 6 than the HFpEF group(P<0.001).According to the ROC curves,HFA-PEFF and H2FPEF scores demonstrated high perform-ance in diagnosing all HFpEF patients,with the area under the curve(AUC)of 0.892 and 0.922 and the opti-mal cut-offs of 4 and 4,respectively.The HFA-PEFF score showed similar performance in diagnosing HFpEF and HFpEF-AF,with the AUC of 0.899 and 0.911,respectively.The H2FPEF score had higher performance in di-agnosing HFpEF-AF(AUC of approximately 1.000)and low performance in diagnosing HFpEF(AUC of 0.885).Conclusions The HFA-PEFF score is applicable in the diagnosis of both HFpEF and HFpEF-AF.The H2FPEF score may underestimate HFpEF in Chinese patients,and its applicability in the Chinese patients with HFpEF alone remains to be investigated.关键词
射血分数保留的心力衰竭/心房颤动/H2FPEF评分/HFA-PEFF评分Key words
heart failure with preserved ejection fraction/atrial fibrillation/H2 FPEF score/HFA-PEFF score分类
医药卫生引用本文复制引用
贾晓艳,刘离香,王东伟,马西文,刘永铭..H2FPEF和HFA-PEFF评分在我国射血分数保留心力衰竭及射血分数保留心力衰竭合并心房颤动患者中的适用性分析[J].中国医学科学院学报,2024,46(2):154-160,7.基金项目
甘肃省重点研发计划(20YF8FA079) （20YF8FA079）
