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结核病非定点医疗机构肺结核漏诊及影响因素分析OA北大核心CSTPCD

The underdiagnosis and risk factors of pulmonary tuberculosis in non-designated medical institutions

中文摘要英文摘要

目的 了解2022年全国结核病非定点医疗机构肺结核漏诊情况及其影响因素,为进一步提高和改进结核病防治工作质量提供依据.方法 基于"2022年全国肺结核诊断和报告质量专项调查"的横断面调查数据,以全国84家非定点医疗机构诊断且经专家组复核的2 179例肺结核患者为研究对象,对肺结核漏诊情况进行分析,采用单因素和多因素Lo-gistic 回归模型分析漏诊的影响因素.结果 在2 179例肺结核患者中,漏诊332例,肺结核漏诊率为15.2%;多因素Lo-gistic 回归 分析结 果显示,非三级医疗机构(OR=1.513,95%CI=1.156~1.980)、年龄0~<15岁(OR=4.987,95%CI=1.790~13.888)、仅咳嗽(OR=1.818,95%CI=1.296~2.550)、单一症状(OR=1.984,95%CI=1.278~3.081)、病原学结果为阴性(OR=7.560,95%CI=3.931~14.540)、无病原学结果(OR=7.834,95%CI=4.151~14.785)、住院患者(OR=1.846,95%CI=1.403~2.429)是肺结核漏诊的危险因素.结论 我国非定点医疗机构的肺结核漏诊率较高,漏诊的发生与医疗机构、年龄、症状、病原学结果、就诊方式有关,应根据上述可能的影响因素制定预防措施来提高诊断质量.

Objective To understand the underdiagnosis of pulmonary tuberculosis(PTB)in non-designated TB medical institutions in 2022 and its influencing factors,providing a basis for further improving the quality of national tuberculosis(TB)prevention and control work.Methods Based on the cross-sectional survey data collected from National PTB Diagnosis and Report Quality Investigation in 2022,2 179 PTB cases diagnosed by 84 non-designated medical institutions and reviewed by expert groups were involved to analyze the diagnosis of pulmonary tuberculosis.Univariable and multivariable Logistic regression models were used to analyze the risk factors of underdiagnosis.Results Among 2 179 PTB patients,332 cases were not diagnosed as PTB(15.2%).Multiple Logistic regression analysis showed that non-tertiary medical institutions(OR=1.513,95%CI=1.156-1.980)、aged 0~<15 years(OR=4.987,95%CI=1.790-13.888)、only cough(OR=1.818,95%CI=1.296-2.550)、single symptom(OR=1.984,95%CI=1.278-3.081)、with nagetive bacteriological results(OR=7.560,95%CI=3.931-14.540)、no bacterialogical results(OR=7.834,95%CI=4.151-14.785)、visitingas inpatients(OR=1.846,95%CI=1.403-2.429)were risk factors of underdiagnosis.Conclusions The proportion of underdiagnosis of PTB in non-designated medical institutions in China was high,and the occurrence of underdiagnosis was related to medical institutions,age,symptoms,pathogen results and treatment methods.Preventive activities should be formulated according to the above possible influencing factors to improve the quality of diagnosis.

阿依奴尔·买买提依不拉音;李玉红;李涛;刘小秋;张慧

中国疾病预防控制中心结核病预防控制中心,北京 102206中国疾病预防控制中心结核病预防控制中心,北京 102206||中国疾病预防控制中心传染病溯源预警与智能决策全国重点实验室,北京 102206

非定点医疗机构肺结核漏诊影响因素

Non-designated medical institutionsTuberculosisUnderdiagnosisInfluencing factors

《中国医学前沿杂志(电子版)》 2024 (003)

16-21 / 6

Tuberculosis Prevention and Control Project of 2024(2428),"13th Five-Year Plan"National Science and Technology Major Project(2017ZX10201302) 2024年结核病预防控制项目结核业务日常运转(2428);"十三五"国家科技重大专项(2017ZX10201302)

10.12037/YXQY.2024.03-04

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