中国医学前沿杂志（电子版）2024，Vol.16Issue(3)：50-55,6.DOI:10.12037/YXQY.2024.03-09
心血管疾病患者的日常体力活动时间与最大脂肪氧化的关系
The association between daily physical activity time and maximal fat oxidation in patients with cardiovascular disease
摘要
Abstract
Objective To explore the relationship between daily physical activity time and maximal fat oxidation in patients with cardiovascular disease.Methods This was a cross-sectional study.Cardiovascular disease patients who underwent cardiopulmonary exercise test(CPET)in Beijing Hospital from April of 2021 to December of 2022 were included.Clinical data and CPET data were collected while International Physical Activity Questionnaire was used to investigate the physical activity time of the patients.Oxygen uptake(VO2),VO2 accounted for predicted maximum value,oxygen pulse and VE/VCO2 on the time of maximal fat oxidation,anaerobic threshold and peak time were recorded.Physical activity time was divided into four groups according to four quadrants(P0-P25,＞P25-P50,＞P50-P75,＞P75-P100)and CPET parameters were compared between those groups.CPET parameters were also compared between four Weber cardiac function groups(Weber A,B,C and D grade).Pearson simple correlation analysis was used to explore the relationship between daily physical activity time and maximal fat oxidation.Results A total of 180 patients were finally enrolled.There were 100 male and 80 female patients with an average age of(62.76±10.98)years old.Maximal fat oxidation and FATmax(VO2 at the time of maximal fat oxidation accounted for predicted maximum V02)did not show difference in four physical activity time groups.VE/VCO2 on maximal fat oxidation(P=0.021),VE/VCO2 on aerobic threshold(P=0.006)and peak VE/VCO2(P＜0.001)showed significant difference in four physical activity time groups.Maximal fat oxidation(P＜0.001),FATmax(P＜0.001),oxygen pulse on maximal fat oxidation(P＜0.001),and VE/VCO2 on maximal fat oxidation(P=0.002)were significant different between four heart function groups according Weber classification.Pearson correlation analysis showed that physical activity time was not significant related with maximal fat oxidation(P=0.658),FATmax(P=0.754)and VE/VCO2 on maximal fat oxidation(P=0.054),but significant related with VE/VCO2 on aerobic threshold(P=0.033)and VE/VCO2 on peak time(P=0.010).Conclusions In cardiovascular disease patients,daily physical activity time may not be correlated with maximal fat oxidation and FATmax,but may be correlated with VE/VCO2.Maximal fat oxidation may exist difference in the patients with different cardiac function.The worse cardiac function,the lower maximal fat oxidation and earlier occurrence time.关键词
心血管疾病/运动心肺测试/体力活动/最大脂肪氧化Key words
Cardiovascular disease/Cardiopulmonary exercise test/Physical activity/Fat oxidation引用本文复制引用
贾娜,夏辰兮,黄铖,孟旭阳,张倩,巫华兰,周济红,汪芳..心血管疾病患者的日常体力活动时间与最大脂肪氧化的关系[J].中国医学前沿杂志（电子版）,2024,16(3):50-55,6.基金项目
科技部国家重点研发计划(2020YFC2008106) （2020YFC2008106）
中央高水平医院临床科研业务费(BJ-2022-117) National Key Research and Development Program of China(2020YFC2008106),National High Level Hospital Clinical Research Funding(BJ-2022-117) （BJ-2022-117）
