中国肿瘤外科杂志2024，Vol.16Issue(2)：116-121,6.DOI:10.3969/j.issn.1674-4136.2024.02.003
江苏省农村地区居民食管癌及癌前病变影响因素分析
Analysis of influencing factors of esophageal cancer and precancerous lesions in rural residents of Jiangsu province
摘要
Abstract
Objective To investigate the detection and influencing factors of esophageal cancer and precancerous lesions in the rural areas of Jiangsu province,and provide theoretical basis for esophageal cancer prevention.Methods The permanent residents aged 40-69 years old who participated in the Early diagnosis and early treatment of upper digestive tract cancer in rural areas of Jiangsu province program from January 2017 to December 2022 were selected.A total of 51,198 residents aged 40-69 years old were selected as the research subjects.Risk factors questionnaire,endoscopy,and tissue biopsy were carried out to determine the precancerous lesions or esophageal cancer according to the pathological diagnosis.SPSS 22.0 software was used for chi-square test.Multinomial logistic regression was used to analyze the influencing factors of esophageal precancerous lesions and esophageal cancer.Results 1,279 cases of precancerous lesions and 741 cases of esophageal cancer were detected in 51,198 subjects(2.50%and 1.45%,respectively).Multinomial logistic regression analysis showed that high school education level or above(OR= 0.81,95%CI:0.66～0.98),a household income of over 50,000 yuan(OR=0.82,95%CI:0.73～0.93),and eating fresh fruit once or twice a week(OR= 0.70,95%CI:0.52～0.93)were low risk factors of esophageal precancerous lesions;Male(OR=1.45,95%CI:1.27～1.65),age(OR=5.35,95%CI:4.22～6.79),eating pickled food(＜twice/week:OR= 1.80,95%CI:1.42～2.28;≥twice/week:OR= 3.01,95%CI:2.35～3.87),esophagitis(OR=1.65,95%CI:1.19～2.31)and geting angry during meals(OR=2.43,95%CI:2.07～2.85)were high risk factors of esophageal precancerous lesions;A household income of over 50 000 yuan was a low risk factor of esophageal cancer(OR=0.74,95%CI:0.64～0.86),male(OR=1.64,95%CI:1.38～1.95),age(OR=5.54,95%CI:4.11～7.46),eating moldy food once or twice a week(OR=1.87,95%CI:1.38～2.54),sophagitis(OR=1.86,95%CI:1.22～2.86),and getting angry during meals(OR=2.95,95%CI:2.37～3.67)were high risk factors of esophageal cancer.Conclusions The detection rate of esophageal cancer and precancerous lesions in rural areas of Jiangsu province is relatively high.Therefore,it is necessary to strengthen the promotion of esophageal cancer health knowledge among males,the elderly,people with a history of esophagitis and poor eating habits,so as to reduce the risk of esophageal cancer.关键词
食管癌/癌前病变/危险因素/无序多分类logistic回归分析Key words
Esophageal Cancer/Precancerous Lesions/Risk factors/Multinomial logistic regression analysis引用本文复制引用
刘付东,吴玲玲,缪伟刚,韩仁强,苏健,周金意,罗鹏飞..江苏省农村地区居民食管癌及癌前病变影响因素分析[J].中国肿瘤外科杂志,2024,16(2):116-121,6.基金项目
中国消化道早癌医师共同成长计划科研项目(GTCZ-2020-JS-32-0002) （GTCZ-2020-JS-32-0002）
盐城市医学科技发展计划项目(YK2021033) （YK2021033）
