中国肿瘤外科杂志2024，Vol.16Issue(2)：122-125,4.DOI:10.3969/j.issn.1674-4136.2024.02.004
桥小脑角脑膜瘤的显微外科治疗及疗效影响因素分析
Microsurgical treatment and analysis of therapeutic efficacy factors for cerebellopontine angle meningiomas
摘要
Abstract
Objective To explore the strategy of microsurgical treatment for cerebellopontine angle(CPA)meningiomas and to analyze the influencing factors of efficacy.Methods A retrospective review was performed on 137 patients with CPA meningiomas who were consecutively admitted to the Department of Neurosurgery,The First Affiliated Hospital of Nanjing Medical University,from April 2009 to May 2019. The extent of tumor resection was assessed using the Simpson classification.Karnofsky performance status(KPS)scale was used to evaluate the patients. outcomes.Results Among the 137 patients,132 patients underwent tumor resection through suboccipital retrosigmoid approach,and 5 patients underwent tumor resection through subtemporal combined with suboccipital retrosigmoid approach.Simpson Ⅰ-Ⅱ resection was achieved in 122(89.1%)cases,Ⅲ in 11(8%)cases,and Ⅳ in 4(2.9%)cases.All patients were followed up and postoperative follow-up duration was 72.4±20.8 months.Tumor recurrence and progression were identified in 2 cases and 1 case respectively.The KPS at the last visit was 92.3±13.1,which is higher than that at discharge(86.9±9.4)and before operation(75.8±10.3)(both P＜0.001).Univariate analysis indicated that the tumor types(P=0.013),the maximum diameter of the tumor(P=0.023),the peritumoral edema(P=0.005),and the incomplete arachnoid interface(P=0.030)are the risk factors influencing total resection.Conclusions Most CPA meningiomas can be removed through suboccipital retrosigmoid approach.Total resection seems to be easier to be achieved when the tumor is non-convexity type,with a small size,intact arachnoid interface,and without peritumoral edema.关键词
桥小脑角/脑膜瘤/枕下乙状窦后入路/危险因素Key words
Cerebellopontine angle/Meningiomas/Suboccipital retrosigmoid approach/Risk factors引用本文复制引用
徐修鹏,刘宁..桥小脑角脑膜瘤的显微外科治疗及疗效影响因素分析[J].中国肿瘤外科杂志,2024,16(2):122-125,4.基金项目
国家自然科学基金青年项目(82203767) （82203767）
江苏省自然科学基金(BK20201077) （BK20201077）
江苏省科教能力提升工程(ZDXK202225) （ZDXK202225）
