原发性甲状旁腺功能亢进症-棕色瘤-骨饥饿综合征OA北大核心CSTPCD

Hungry bone syndrome is a relatively uncommon but severe postoperative complication of primary hy-perparathyroidism,most frequently observed in patients with severe preoperative bone involvement.A 45-year-old female patient was diagnosed with severe primary hyperparathyroidism.The patient exhibited pronounced preoperative bone pain.Preoperative biochemical examinations revealed remarkedly elevated serum bone turnover markers,and imaging studies in-dicated multiple bone destruction and brown tumor.Following the surgical resection of parathyroid lesions,the patient de-veloped a severe and persistent hypocalcemia,characterized by the perioral and limb paresthesia.Hungry bone syndrome was suspected,and the patient was treated with a high dose calcium and active vitamin D,resulting in symptoms allevia-tion and normalization of serum calcium levels.