中华骨质疏松和骨矿盐疾病杂志2024，Vol.17Issue(1)：50-55,6.DOI:10.3969/j.issn.1674-2591.2024.01.006
原发性甲状旁腺功能亢进症-棕色瘤-骨饥饿综合征
Primary hyperparathyroidism-brown tumor-hungry bone syndrome
贾觉睿智 1刘宏颖 1段炼 1姜艳 1李梅 1夏维波 1邢小平 1王鸥1
作者信息
- 1. 100730 北京,中国医学科学院 北京协和医学院 北京协和医院内分泌科,卫健委内分泌重点实验室
- 折叠
摘要
Abstract
Hungry bone syndrome is a relatively uncommon but severe postoperative complication of primary hy-perparathyroidism,most frequently observed in patients with severe preoperative bone involvement.A 45-year-old female patient was diagnosed with severe primary hyperparathyroidism.The patient exhibited pronounced preoperative bone pain.Preoperative biochemical examinations revealed remarkedly elevated serum bone turnover markers,and imaging studies in-dicated multiple bone destruction and brown tumor.Following the surgical resection of parathyroid lesions,the patient de-veloped a severe and persistent hypocalcemia,characterized by the perioral and limb paresthesia.Hungry bone syndrome was suspected,and the patient was treated with a high dose calcium and active vitamin D,resulting in symptoms allevia-tion and normalization of serum calcium levels.关键词
原发性甲状旁腺功能亢进症/棕色瘤/骨饥饿综合征Key words
primary hyperparathyroidism/brown tumor/hungry bone syndrome分类
医药卫生引用本文复制引用
贾觉睿智,刘宏颖,段炼,姜艳,李梅,夏维波,邢小平,王鸥..原发性甲状旁腺功能亢进症-棕色瘤-骨饥饿综合征[J].中华骨质疏松和骨矿盐疾病杂志,2024,17(1):50-55,6.
