中华骨质疏松和骨矿盐疾病杂志2024，Vol.17Issue(1)：67-74,8.DOI:10.3969/j.issn.1674-2591.2024.01.009
LncRNA与信号通路在骨质疏松症发生机制中的研究进展
Research progress of lncRNA and signaling pathways in osteoporosis
摘要
Abstract
Osteoporosis is a common bone disease,in which the imbalance of osteogenic differentiation and oste-oclastic differentiation of bone metabolism is closely related to the pathogenesis of osteoporosis.In recent years,long chain non-coding RNAs have been found to play an important role in the development of osteoporosis and gradually become the focus of research on the mechanism of OP occurrence.In this article,the overview of lncRNA and their interactions with related signaling pathways,in the mechanism of osteoporosis were reviewed from the perspectives of osteoblast differentia-tion osteoclast differentiation,so as to provide new ideas and strategies for the exploration of new diagnostic and therapeu-tic targets for osteoporosis in the future.关键词
lncRNA/骨质疏松/信号通路/成骨分化/破骨分化Key words
long non-coding RNA/osteoporosis/signaling pathways/osteoblast differentiation/osteoclast dif-ferentiation分类
医药卫生引用本文复制引用
杨城,李玮民,冉栋成,王春庆..LncRNA与信号通路在骨质疏松症发生机制中的研究进展[J].中华骨质疏松和骨矿盐疾病杂志,2024,17(1):67-74,8.基金项目
国家自然科学基金(8206060273) （8206060273）
