孙颖 1李志明 1康宁 1王文雯 1王爱丽 1李仝1
作者信息
- 1. 100029 北京,北京中医药大学第三附属医院肿瘤血液科
- 折叠
摘要
Abstract
Objective To explore the therapeutic effect of"jian pi yi qi yang xue zhi tong"for treating bone metastasis of breast cancer and the clinical effect of improving pain symptoms.Methods A total of 80 patients with bone metastases from breast cancer were admitted.They were randomly divided into an observation group and a control group according to the random-number-table method.The control group was treated with zoledronic acid,whereas the observation group was treated with jian pi yi qi yang xue zhi tong prescriptions based on the control group.We compared the differences in the effects of different treatment plans on patients'pain symptoms,physical condition,and quality of life,as well as TNF-α,IL-6,and CRP levels.Results No significant difference was found in pain scores,physical condition scores,sleep quality scores,and quality of life scores,as well as CRP,IL-6,and TNF-α levels between the two groups of patients before treatment(all P>0.05).At one,two,and four months after treatment,the pain scores of both groups of patients decreased,with the observation group having lower scores than the control group(P<0.05).The total pain-relief rate of the observation group was higher than that of the control group(P<0.05).After treatment,the sleep quality scores and the levels of CRP,IL-6,and TNF-α decreased,with the observation group having lower values than the control group(P<0.05).The physical condition scores and the quality of life scores of both groups improved,with the observation group having higher values than the control group(P<0.05).Conclusion In patients with bone metastases from breast cancer,oral treatment with jian pi yi qi yang xue zhi tong prescription has a significant effect.It substantially improves the pain symptoms,enhances the quality of sleep and life of patients,and reduces the levels of CRP,IL-6,and TNF-α.关键词
乳腺癌/骨转移/中药治疗/疼痛/生活质量Key words
Breast cancer/Bone metastasis/Traditional Chinese medicine treatment/Pain/Quality of life分类
医药卫生
