肿瘤防治研究2024，Vol.51Issue(4)：278-283,6.DOI:10.3971/j.issn.1000-8578.2024.23.1094
线粒体在肺癌发生中的作用机制及治疗研究进展
Research Progress in Mitochondrial Treatment and Mechanism in Occurrence of Lung Cancer
摘要
Abstract
Lung cancer is characterized by high incidence and mortality rates and invasiveness,and its occurrence and development are influenced by various factors.Mitochondria,as ubiquitous organelles in the human body,regulate cellular processes,such as metabolism,signal transduction,oxidative stress,and genomic instability,thereby affecting the initiation and progression of lung cancer.This article summarizes the recent research progress on mitochondrial-targeted drugs,mitochondrial transfer,and mitochondrial gene therapy for lung cancer treatment.This work also discusses the principles and prospects of mitochondrial therapy to provide new insights for lung cancer treatment.关键词
线粒体/肺癌/作用机制/治疗Key words
Mitochondria/Lung cancer/Mechanism/Treatment分类
医药卫生引用本文复制引用
吴发胜,张晖,谢家童,李建福,陈慧,鲁世金..线粒体在肺癌发生中的作用机制及治疗研究进展[J].肿瘤防治研究,2024,51(4):278-283,6.基金项目
National Natural Science Foundation of China(No.82260944) （No.82260944）
Doctoral Research Project(No.2018BS056) 国家自然科学基金(82260944) （No.2018BS056）
博士科研项目(2018BS056) （2018BS056）
