中国中西医结合杂志2024，Vol.44Issue(4)：426-431,6.DOI:10.7661/j.cjim.20240308.041
儿童非重型再生障碍性贫血中医证候分布研究
Study on Distribution of Chinese Medicine Syndromes in Children with Non-severe Aplastic Anemia
摘要
Abstract
Objective To explore the distribution of Chinese medicine(CM)syndromes of children with non-severe aplastic anemia(NSAA),and to provide reference for CM clinical sydrome differentiation and classification of NSAA.Methods Children diagnosed with NSAA between January 2019 and December 2021 were recruited in this study.A questionnaire was developed to investigate the elements of syndrome and clinical information was collected accordingly.Factor analysis and cluster analysis were used to explore the distribution of CM syndromes among children with NSAA.Results A total of 368 patients were recruited in this study,and 54 CM syndromes were collected with a frequency of＞15％.Factor analysis resulted in the identification of 16 common factors.In terms of disease location of NSAA,the main syndrome elements were Pi,Shen and Gan,while the disease nature syndrome elements were mainly qi deficiency,blood deficiency,yin deficiency,yang deficiency and phlegm-dampness.Further cluster analysis of the 16 common factors revealed that CM syndromes could be summarized into five categories:deficiency of Pi-qi,qi and blood deficiency,Shen-yin deficiency,Shen-yang deficiency,and Shen yin-yang deficiency.Conclusions The main disease location of children with NSAA was in the Pi,Shen and Gan.The CM syndromes mainly include five types which were deficiency of Pi-qi,qi and blood deficiency,Shen-yin deficiency,Shen-yang deficiency,and Shen yin-yang deficiency关键词
儿童非重型再生障碍性贫血/证素/中医证候/因子分析/聚类分析Key words
children with non-severeaplastic anemia/syndrome element/CM syndrome/factor analysis/cluster analysis引用本文复制引用
黄莉荣,薛征,陈静,尤焱南,崔雯,王雅娟..儿童非重型再生障碍性贫血中医证候分布研究[J].中国中西医结合杂志,2024,44(4):426-431,6.基金项目
国家自然科学基金资助项目(No.82274576) （No.82274576）
儿科中西医协同诊疗网络建设项目[No.ZY(2021-2023)-0206-04] （2021-2023）
海派中医徐氏儿科学术传承及创新团队建设项目(No.2021LPTD-006) （No.2021LPTD-006）
