中国现代中药2024，Vol.26Issue(3)：479-486,8.DOI:10.13313/j.issn.1673-4890.20231106002
电子束辐照对西藏荨麻主要活性成分及灭菌效果的影响
Impact of Electron Beam Irradiation on the Main Active Ingredients of Urtica tibetica and Its Sterilization Effect
摘要
Abstract
Objective:To explore the impact of electron beam irradiation on the main active ingredients of Urtica tibetica W.T.Wang and its sterilization effect.Methods:The U.tibetica powder was treated with electron beam irradiation at doses of 0,2,4,6,8,and 10 kGy.The characteristics,total flavonoids,chlorogenic acid,isovitexin,and astragaloside,fingerprints,and microbial levels of the samples before and after irradiation were compared.Results:After different doses of electron beam irradiation,there were no significant changes in the characteristics,total flavonoids and chlorogenic acid,isovitexin,and astragaloside of U.Tibetica powder.The similarity of the fingerprint reached 0.996 or above,and the number of bacterial colonies and the total number of fungal and yeast colonies decreased(P<0.01).When the irradiation dose reached 6 kGy,the microbial levels met the requirements of the Chinese Pharmacopoeia(2020 edition).Conclusion:The electron beam irradiation at different doses had no significant impact on the main active ingredients of U.tibetica,and excellent sterilization effect was observed at 6 kGy.This paper provided a reference for the irradiation sterilization technology of U.tibetica and its preparations.关键词
西藏荨麻/电子束辐照/性状鉴别/指纹图谱/含量测定Key words
Urtica tibetica W.T.Wang/electron beam irradiation/character identification/fingerprint/content determination分类
医药卫生引用本文复制引用
张赫林,谢和兵,王弼聪,尼玛次仁,白玛旦增..电子束辐照对西藏荨麻主要活性成分及灭菌效果的影响[J].中国现代中药,2024,26(3):479-486,8.基金项目
2022年日喀则市区域科技协同创新专项(QYXTZX-RKZ2022-07) （QYXTZX-RKZ2022-07）
