中国现代中药2024，Vol.26Issue(3)：550-565,16.DOI:10.13313/j.issn.1673-4890.20230906005
经典名方升陷汤的研究进展及质量标志物的预测分析
Research Progress on Classical Prescription Shengxian Decoction and Predictive Analysis of Its Q-markers
摘要
Abstract
Classical prescription Shengxian Decoction,composed of Radix Astragali,Rhizoma Anemarrhenae,Radix Bupleuri,Rhizoma Cimicifugae and Radix Platycodonis,is mainly used to treat the sinking of pectoral qi.Clinically,the prescription is widely used for the treatment of circulatory and respiratory system diseases.In this paper,the research progress on the chemical component,pharmacological action and clinical application of Shengxian Decoction in recent years was summarized and analyzed,and the quality markers(Q-markers)were predicted from five aspects:quality transfer and traceability,component measurability,component effectiveness,component specificity and compound compatibility.The result showed that astragaloside Ⅳ,calycosin-7-O-β-D-glucoside,caylcosin,ononin,formononetin,saikosaponin A,saikosaponin D,mangiferin,timosaponin B-Ⅱ,ferulic acid,isoferulic acid and platycodon D could be used as Q-markers for Shengxian Decoction,which provided scientific basis for the establishment of the quality control system and the whole-process quality traceability system of the prescription.关键词
升陷汤/质量标志物/化学成分/药理作用/临床应用Key words
Shengxian Decoction/quality marker/chemical component/pharmacological action/clinical application分类
中医学引用本文复制引用
周浩明,乐世俊,刘文娟,崔东晓,付瑞嘉,唐于平..经典名方升陷汤的研究进展及质量标志物的预测分析[J].中国现代中药,2024,26(3):550-565,16.基金项目
陕西省中医药管理局基于大数据的中医药防治新冠真实世界研究与应用(ZYJXG-L23001) （ZYJXG-L23001）
