遵义医科大学学报2024，Vol.47Issue(4)：408-415,8.
EB病毒相关性噬血细胞综合征的治疗进展
Progress in the treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis
摘要
Abstract
Hemophagocytic lymphohistiocytosis(HLH)is a severe inflammatory syndrome caused by the exces-sive proliferation and activation of T cells and macrophages.This disease progresses rapidly with a high mortality rate.Although the HLH-1994 and HLH-2004 protocols have significantly improved patient survival rates,there are still therapeutic challenges.Epstein-Barr virus-associated HLH(EBV-HLH)is the most common subtype of HLH in Asian children.Although the outcome of pediatric EBV-HLH is superior to other subtypes,about 20％～30％of patients experience relapse or arerefractory to the treatment.This review provides an overview of the ad-vancements in the treatment for EBV-HLH.关键词
EB病毒/噬血细胞综合征/治疗/预后Key words
epstein-barr virus/hemophagocytic syndrome/treatment/prognosis分类
医药卫生引用本文复制引用
邢源,陈艳,徐晓军..EB病毒相关性噬血细胞综合征的治疗进展[J].遵义医科大学学报,2024,47(4):408-415,8.基金项目
国家自然科学基金面上项目(NO:81970122). （NO:81970122）
