腹腔镜外科杂志2024，Vol.29Issue(3)：179-183,5.DOI:10.13499/j.cnki.fqjwkzz.2024.03.179
单孔与多孔亚肺叶切除术治疗早期非小细胞肺癌的疗效探讨
Curative effect discussion of single-port and multi-port video-assisted thoracic surgery sublobectomy on early non-small cell lung caicinoma
摘要
Abstract
Objective:To explore the curative effect of single-port and multi-port video-assisted thoracic surgery sublobectomy on early non-small cell lung cancer.Methods:A total of 150 patients with early non-small cell lung cancer admitted between Jan.2020 and Dec.2022 were enrolled.According to the random number table method,they were divided into single-port group(single-port video-assisted thoracic surgery sublobectomy),two-port group(two-port video-assisted thoracic surgery sublobectomy)and three-port group(three-port video-assisted thoracic surgery sublobectomy),with 50 cases in each group.The surgical situations,postoperative recovery,hospital stay,incidence of postoperative complications,scores of visual analogue scale at 1 d and 3 d after surgery,levels of serum tumor necrosis factor-α,interleukin-6 and hypersensitive C-reactive protein before surgery and 3 d after surgery,forced expiratory volume in one second,forced vital capacity and maximal voluntary ventilation at 1 d before surgery and 3 months after surgery were compared among the three groups.Results:Compared with two-port group and three-port group,in single-port group intraoperative blood loss and postoperative thoracic drainage volume were less,pain scores of visual analogue scale were lower at 1 d and 3 d after surgery,postopera-tive drainage time and hospital stay were shorter(P<0.05).At 3 d after surgery,levels of tumor necrosis factor-α,interleukin-6 and hypersensitive C-reactive protein in the single-port group were lower than those in the two-port group and the three-port group(P<0.05).There were no significant differences in forced expiratory volume in one second,forced vital capacity and maximal voluntary ven-tilation among the three groups at 1 month after surgery(P>0.05).The incidence of postoperative complications in the single-port group was6.00%,which was significantly lower than that in the two-port group and the three-port group(20.00%,24.00%,P<0.05).Conclusions:The surgical effect of both single-port and multi-port video-assisted thoracic surgery sublobectomy is similar for patients with early non-small cell lung cancer.The single-port video-assisted thoracic surgery sublobectomy can shorten postoperative drainage time and hospitalization time,and relieve postoperative pain and inflammatory response.关键词
早期非小细胞肺癌/亚肺叶切除术/胸腔镜检查/单孔/多孔Key words
Early non-small cell lung carcinoma/Pulmonary sublobectomy/Thoracoscopy/Single-port/Multi-port分类
医药卫生引用本文复制引用
王代平,王世平,何学东,马伟,钟庆..单孔与多孔亚肺叶切除术治疗早期非小细胞肺癌的疗效探讨[J].腹腔镜外科杂志,2024,29(3):179-183,5.基金项目
四川省医学科研课题计划项目(S20037) （S20037）
简阳市人民医院课题项目(JY202307) （JY202307）
