广西医科大学学报2024，Vol.41Issue(4)：590-597,8.DOI:10.16190/j.cnki.45-1211/r.2024.04.016
基于便携式近红外光谱仪的土茯苓配方颗粒一致性评价及定量分析方法
Consistency evaluation and quantitative analysis of Smilax glabra formula granules based on portable near infrared spectrometer
摘要
Abstract
Objective:To establish a rapid detection method of consistency evaluation and astilbin content as an index component for Smilax glabra formula granules.Methods:Based on portable near infrared spectrometer,the consistency evaluation model was established by using software OMNIC,and a quantitative model of astilbin was established by combining partial least squares(PLS)and support vector regression(SVR).Results:The fin-gerprint characteristics of 55 batches of Smilax glabra formula granules were similar,and the similarity was 0.9928-0.9996.The PLS and SVR quantitative models of astilbin showed that the correlation coefficient(RP)of prediction set was 0.8483 and 0.8990,respectively,and the root mean square error of prediction(RMSEP)was 1.809 and 1.481,respectively.Conclusion:Based on portable near infrared spectrometer,a rapid evaluation meth-od of Smilax glabra formula granules is established in this study.The established model can predict the content of index components quickly and non-destructively,which provides some reference for the quality control of Smilax glabraformula granules.关键词
近红外光谱/土茯苓配方颗粒/落新妇苷/一致性评价/定量分析Key words
near infrared spectroscopy/Smilax glabra formula granules/astilbin/consistency evaluation/quanti-tative analysis分类
医药卫生引用本文复制引用
钟欣瑜,秦鑫,韦锦斌,韦红言,叶善洋,苏志恒,梁永红..基于便携式近红外光谱仪的土茯苓配方颗粒一致性评价及定量分析方法[J].广西医科大学学报,2024,41(4):590-597,8.基金项目
国家自然科学基金地区项目(No.82060763) （No.82060763）
广西科技重大专项资助项目(No.2022JBGS042) （No.2022JBGS042）
